{"id":32070,"date":"2021-07-28T09:30:50","date_gmt":"2021-07-28T08:30:50","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=32070"},"modified":"2021-07-28T09:38:10","modified_gmt":"2021-07-28T08:38:10","slug":"research-evaluating-routine-blood-tests-according-to-clinical-symptoms-diagnostic-criteria-in-individuals-with-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/research-evaluating-routine-blood-tests-according-to-clinical-symptoms-diagnostic-criteria-in-individuals-with-me-cfs\/","title":{"rendered":"Research: Evaluating routine blood tests according to clinical symptoms & diagnostic criteria in individuals with ME\/CFS"},"content":{"rendered":"

Evaluating routine blood tests according to clinical symptoms and diagnostic criteria in individuals with Myalgic Encephalomyelitis \/Chronic Fatigue Syndrome<\/a>, by Ingrid H. Baklund, Toril Dammen, Torbjorn Age Moum, Wenche Kristiansen, Daysi Sosa Duarte, Jesus Castro-Marrero, Ingrid Bergliot Helland, Elin Bolle Strand in<\/span>\u00a0Journal of Clinical<\/em> Medicine<\/em>\u00a0Vol 10, #14, p 3105, July 14, 2021<\/h3>\n

 <\/p>\n

Research abstract:<\/strong><\/h3>\n

\"\"There is a lack of research regarding blood tests within individuals with Myalgic Encephalomyelitis\/Chronic Fatigue Syndrome (ME\/CFS) and between patients and healthy controls. We aimed to compare results of routine blood tests between patients and healthy controls.<\/p>\n

Data from 149 patients diagnosed with ME\/CFS based on clinical and psychiatric evaluation as well as on the DePaul Symptom Questionnaire, and data from\u00a0264 healthy controls recruited from blood donors were compared.<\/p>\n

One-way ANCOVA<\/a> was conducted to examine differences between ME\/CFS patients and healthy controls, adjusting for age and gender.<\/p>\n

Patients had higher sedimentation rate<\/a><\/strong> (mean difference: 1.38, 95% CI: 0.045 to 2.714), leukocytes (mean difference: 0.59, 95% CI: 0.248 to 0.932), lymphocytes (mean difference: 0.27, 95% CI: 0.145 to 0.395), neutrophils (mean\u00a0difference: 0.34, 95% CI: 0.0 89 to 0.591), monocytes (mean difference:\u00a00.34, 95% CI: 0.309 to 0.371), ferritin (mean difference: 28.13, 95% CI:\u00a0-1.41 to 57.672), vitamin B12 (mean difference: 83.43, 95% CI: 62.89 to 124.211), calcium (mean difference: 0.02, 95% CI: -0.02 to 0.06), alanine transaminase (mean difference: 3.30, 95% CI: -1.37 to -7.971), low-density lipoproteins (mean difference: 0.45, 95% CI: 0.104 to 0.796), and total proteins (mean difference: 1.53, 95% CI: -0.945 to\u00a04.005) than control subjects.<\/p>\n

The patients had lower potassium levels<\/strong><\/a> (mean difference: 0.11, 95% CI: 0.056 to 0.164), creatinine (mean\u00a0difference: 2.60, 95% CI: 0.126 to 5.074) and creatine kinase (CK) (mean\u00a0difference: 37.57, 95% CI: -0.282 to 75.422) compared to the healthy controls.<\/p>\n

Lower CK and creatinine levels<\/a><\/strong> may suggest muscle damage and metabolic abnormalities in ME\/CFS patients.<\/p>\n

Conclusions<\/strong><\/h3>\n

Results of several routine blood tests of ME\/CFS patients differed from those healthy controls. Our findings particularly highlight that decreased creatinine and CK levels may indicate greater muscle damage and metabolic disturbances in ME\/CFS patients and is worthy of future studies. This is also true of results that may indicate a possible low-grade inflammation in ME\/CFS patients.<\/p>\n","protected":false},"excerpt":{"rendered":"

Evaluating routine blood tests according to clinical symptoms and diagnostic criteria in individuals with Myalgic Encephalomyelitis \/Chronic Fatigue Syndrome, by Ingrid H. Baklund, Toril Dammen, Torbjorn Age Moum, Wenche Kristiansen, Daysi Sosa Duarte, Jesus Castro-Marrero, Ingrid Bergliot Helland, Elin Bolle … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[2848,4971,107,6912],"class_list":["post-32070","post","type-post","status-publish","format-standard","hentry","category-news","tag-blood-tests","tag-creatine-kinase","tag-diagnostic-criteria","tag-low-potassium-levels"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8lg","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/32070","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=32070"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/32070\/revisions"}],"predecessor-version":[{"id":32121,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/32070\/revisions\/32121"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=32070"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=32070"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=32070"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}