{"id":33270,"date":"2021-11-10T09:32:42","date_gmt":"2021-11-10T09:32:42","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=33270"},"modified":"2021-11-10T09:36:18","modified_gmt":"2021-11-10T09:36:18","slug":"diagnostic-test-research-saliva-fatigue-biomarker-for-severe-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/diagnostic-test-research-saliva-fatigue-biomarker-for-severe-me-cfs\/","title":{"rendered":"Diagnostic test research: Saliva fatigue biomarker for severe ME\/CFS"},"content":{"rendered":"<h3><a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21641846.2021.1994222\" target=\"_blank\" rel=\"noopener\">Saliva fatigue biomarker index as a marker for severe myalgic encephalomyelitis\/ chronic fatigue syndrome in a community based sample<\/a>, by Leonard A Jason, John Kalns, Alicia Richarte, Ben Z Katz, Chelsea Torres <span style=\"text-decoration: underline;\">in<\/span>\u00a0<em>Fatigue: Biomedicine, Health &amp; Behavior, <\/em>October 27, 2021 [doi\/full\/10.1080\/21641846.2021.1994222]<\/h3>\n<p>&nbsp;<\/p>\n<h3><strong>Research abstract:<\/strong><\/h3>\n<p><strong>Objective<\/strong><\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright size-medium wp-image-12378 lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2017\/03\/jason.jpg?resize=300%2C200&#038;ssl=1\" alt=\"\" width=\"300\" height=\"200\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2017\/03\/jason.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2017\/03\/jason.jpg?resize=150%2C100&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2017\/03\/jason.jpg?resize=768%2C511&amp;ssl=1 768w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2017\/03\/jason.jpg?w=1024&amp;ssl=1 1024w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/200;\" \/>The prevalence of pediatric Myalgic Encephalomyelitis\/ Chronic Fatigue Syndrome (ME\/CFS) has been estimated from an ethnically and sociodemographically diverse community-based random sample of 10,119 youth aged 5-17. We assessed whether a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19712004\/\" target=\"_blank\" rel=\"noopener\">salivary<\/a> biomarker of fatigue could identify youth with ME\/CFS.<\/p>\n<p><strong>Study design<\/strong><\/p>\n<p>We examined the ratio of the concentrations of <a href=\"https:\/\/www.thoughtco.com\/what-is-a-peptide-definition-examples-4177787\" target=\"_blank\" rel=\"noopener\">2 peptide fragments<\/a> in saliva, referred to as the Fatigue Biomarker Index (FBI), in participants from our study diagnosed with ME\/CFS (n=59) and matched controls (n=39).<\/p>\n<p><strong>Results<\/strong><\/p>\n<p>Significant overall differences were found in the FBI between those participants with severe ME\/CFS and those with ME\/CFS and the controls.<\/p>\n<p><strong>Conclusions<\/strong><\/p>\n<p>If confirmed in other populations, the FBI could serve as an objective test to aid in the diagnosis of severe ME\/CFS.<\/p>\n<p><em>Full article behind a paywall<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Saliva fatigue biomarker index as a marker for severe myalgic encephalomyelitis\/ chronic fatigue syndrome in a community based sample, by Leonard A Jason, John Kalns, Alicia Richarte, Ben Z Katz, Chelsea Torres in\u00a0Fatigue: Biomedicine, Health &amp; Behavior, October 27, 2021 &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/diagnostic-test-research-saliva-fatigue-biomarker-for-severe-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[7104,4180,4170,5569,715,7106,7105,2241],"class_list":["post-33270","post","type-post","status-publish","format-standard","hentry","category-news","tag-alicia-richarte","tag-ben-z-katz","tag-biomarker","tag-chelsea-torres","tag-diagnostic-test","tag-fatigue-biomarker-index","tag-john-kalns","tag-prof-leonard-jason"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8EC","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=33270"}],"version-history":[{"count":5,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33270\/revisions"}],"predecessor-version":[{"id":33433,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33270\/revisions\/33433"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=33270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=33270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=33270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}