{"id":33667,"date":"2021-12-09T22:22:50","date_gmt":"2021-12-09T22:22:50","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=33667"},"modified":"2021-12-09T22:24:03","modified_gmt":"2021-12-09T22:24:03","slug":"biomarker-research-the-maintained-attention-assessment-in-patients-affected-by-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/biomarker-research-the-maintained-attention-assessment-in-patients-affected-by-me-cfs\/","title":{"rendered":"Biomarker research: The maintained attention assessment in patients affected by ME\/CFS"},"content":{"rendered":"

The maintained attention assessment in patients affected by Myalgic encephalomyelitis\/ chronic fatigue syndrome: A reliable biomarker?<\/a>, by Inigo Murga, Larraitz Aranburu, Pascual A Gargiulo, Juan-Carlos Gomez-Esteban, Jose-Vicente Lafuente in<\/span> Journal of Translational Medicine\u00a0<\/em>Vol 19, #1, p 494, December 4, 2021<\/h3>\n

 <\/p>\n

Research abstract<\/strong><\/h3>\n

The maintained attention is the cause of great functional limitations in CFS\/ME, a disease that mainly affects women in the central period of life. Cognitive function is explored using the Montreal Cognitive Assessment<\/a>, the maintained attention using the Toulouse-Pieron test<\/a> with which the Global Index of Attention and Perception (GIAP) is obtained, the fatigue using the visual analog scale<\/a> and the perception of effort using the modified Borg scale<\/a>.<\/p>\n

\"\"The final sample were 84 patients (66\u00a0women\/18 men) who met diagnostic criteria (Fukuda-1994, Carruthers-2011) and 22 healthy controls (14 women\/8 men). Most of patients maintain normal cognitive function, showing low or very low attention score in the 70% of patients with a marked cognitive fatigue compared to the control group (p<0.05).<\/p>\n

There were no significant differences between genders in GIAP or fatigue for CFS\/ME; however, sick women perceive cognitive effort higher than men. Deficits in sustained attention and the perception of fatigue, so effort after performing the proposed test are a sensitive and reliable indicator that allows us to substantiate a clinical suspicion and refer patients for further studies in order to confirm or rule out CFS\/ME.<\/p>\n

Conclusion<\/strong><\/h3>\n

General cognition remains preserved in most patients, only a small group of them shows a significant mild cognitive impairment. Maintained attention is clearly deficient, showing a marked fatigability after the Toulouse-Pi\u00e9ron test. The effort was perceived as very hard by both gender, but higher by women.<\/p>\n

This study proposes a simple clinical way to assess maintained attention. Present results support the reliability of maintained attention as biomarker of CFS\/ME. Attention deficit is a significant disability in patients affected of central fatigue.<\/p>\n","protected":false},"excerpt":{"rendered":"

The maintained attention assessment in patients affected by Myalgic encephalomyelitis\/ chronic fatigue syndrome: A reliable biomarker?, by Inigo Murga, Larraitz Aranburu, Pascual A Gargiulo, Juan-Carlos Gomez-Esteban, Jose-Vicente Lafuente in Journal of Translational Medicine\u00a0Vol 19, #1, p 494, December 4, 2021 … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[4170,5154,5155,7072,7155,7153,7156,7154],"class_list":["post-33667","post","type-post","status-publish","format-standard","hentry","category-news","tag-biomarker","tag-inigo-murga","tag-jose-vicente-lafuente","tag-juan-carlos-gomez-esteban","tag-larraitz-aranburu","tag-maintained-attention","tag-pascual-a-gargiulo","tag-toulouse-pieron-test"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8L1","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=33667"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33667\/revisions"}],"predecessor-version":[{"id":33742,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/33667\/revisions\/33742"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=33667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=33667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=33667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}