{"id":34215,"date":"2021-11-25T10:51:26","date_gmt":"2021-11-25T10:51:26","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=34215"},"modified":"2022-09-12T11:15:06","modified_gmt":"2022-09-12T10:15:06","slug":"research-analysis-of-post-covid-19-its-overlap-with-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/research-analysis-of-post-covid-19-its-overlap-with-me-cfs\/","title":{"rendered":"Research: Analysis of post COVID-19 &#038; its overlap with ME\/CFS"},"content":{"rendered":"<h2><strong>Long COVID overlap with ME\/CFS<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<p>A group of researchers from around the world have joined together to analyse long COVID&#8217;s symptom overlap with ME\/CFS.<\/p>\n<h3 class=\"section-title u-h3 u-margin-l-top u-margin-xs-bottom\"><strong>Highlights<\/strong><\/h3>\n<ul>\n<li><strong>Serious side effects and post-infection sequelae have been reported in SARS-CoV-2-infected patients after acute disease phase.<\/strong><\/li>\n<li>Long-COVID patient characteristics and symptoms were compared to myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS).<\/li>\n<li>The onset, progression, and symptom profile of long-COVID patients have considerable overlap with ME\/CFS.<\/li>\n<li>Longitudinal monitoring of COVID-19 patients is warranted to understand the virus long-term effects.<\/li>\n<\/ul>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright size-large wp-image-36680 lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?resize=880%2C715&#038;ssl=1\" alt=\"\" width=\"880\" height=\"715\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?resize=1024%2C832&amp;ssl=1 1024w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?resize=300%2C244&amp;ssl=1 300w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?resize=150%2C122&amp;ssl=1 150w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?resize=768%2C624&amp;ssl=1 768w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/09\/long-COVID-analysis.jpg?w=1091&amp;ssl=1 1091w\" data-sizes=\"(max-width: 880px) 100vw, 880px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 880px; --smush-placeholder-aspect-ratio: 880\/715;\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2090123221002320\" target=\"_blank\" rel=\"noopener\">Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis\/<\/a><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2090123221002320\" target=\"_blank\" rel=\"noopener\"> chronic fatigue syndrome<\/a>, by Olga A Sukocheva, Rebekah Maksoud, Narasimha M Beeraka, SabbaRao V Madhunapantula, Mikhail Sinelnikov, Vladimir N Nikolenko, Margarita E Neganova, Sergey G Klochkov, Mohammad Amjad Kamali, Donald R Staines, Sonya Marshall-Gradisnik <span style=\"text-decoration: underline;\">in<\/span> \u00a0<em>Journal of Advanced Research<\/em>, Volume 40, September 2022, Pages 179-196 [doi.org\/10.1016\/j.jare.2021.11.013] Preprint Nov 2021<\/p>\n<h3><strong>Research abstract<\/strong><\/h3>\n<p><strong>Background<\/strong><\/p>\n<p>The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease\u00a0(COVID-19) triggers the development of numerous pathologies and infection-linked complications and exacerbates existing pathologies in nearly all body systems. Aside from the primarily targeted respiratory organs, adverse SARS-CoV-2 effects were observed in nervous, cardiovascular, gastrointestinal\/metabolic, immune, and other systems in\u00a0COVID-19 survivors. Long-term effects of this viral infection have been recently observed and represent distressing sequelae recognised by the World Health Organisation (WHO) as a distinct clinical entity defined as\u00a0post-COVID-19 condition. Considering the pandemic is still ongoing, more time is required to confirm post COVID-19 condition diagnosis in the\u00a0COVID-19 infected cohorts, although many reported post COVID-19 symptoms overlap with myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS).<\/p>\n<h3><strong>Aims of Review<\/strong><\/h3>\n<p>In this study, COVID-19 clinical presentation and associated post-infection sequelae (post-COVID-19 condition) were reviewed and compared with ME\/CFS symptomatology.<\/p>\n<p><strong>Key Scientific Concepts of Review<\/strong><\/p>\n<p>The onset, progression, and symptom profile of post COVID-19 condition patients have considerable overlap with ME\/CFS. Considering the large scope and range of pro-inflammatory effects of this virus, it is reasonable to expect development of post COVID-19 clinical complications in a proportion of the affected population. There are reports of a later debilitating syndrome onset three months post COVID-19 infection (often described as long-COVID-19), marked by the presence of fatigue, headache, cognitive dysfunction, post-exertional malaise, orthostatic intolerance, and dyspnoea. Acute inflammation, oxidative stress, and increased levels of interleukin-6 (IL-6) and tumor necrosis factor alpha (TNFalpha), have been reported in SARS-CoV-2 infected patients.<\/p>\n<p>Longitudinal monitoring of post COVID-19 patients is warranted to understand the long-term effects of SARS-CoV-2 infection and the pathomechanism of post COVID-19 condition.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Long COVID overlap with ME\/CFS &nbsp; A group of researchers from around the world have joined together to analyse long COVID&#8217;s symptom overlap with ME\/CFS. Highlights Serious side effects and post-infection sequelae have been reported in SARS-CoV-2-infected patients after acute &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/research-analysis-of-post-covid-19-its-overlap-with-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[602,1249,6196,7345,7343,7347,7341,7340,2232,6862,2676,5873,7342,7346,7344],"class_list":["post-34215","post","type-post","status-publish","format-standard","hentry","category-news","tag-assessment-of-symptoms","tag-dr-sonya-marshall-gradisnik","tag-long-covid","tag-margarita-e-neganova","tag-mikhail-sinelnikov","tag-mohammad-amjad-kamali","tag-narasimha-m-beeraka","tag-olga-a-sukocheva","tag-post-infectious-fatigue-syndrome","tag-postacute-sequelae-of-sars-cov-2-infection","tag-prof-donald-staines","tag-rebekah-maksoud","tag-sabbarao-v-madhunapantula","tag-sergey-g-klochkov","tag-vladimir-n-nikolenko"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8TR","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=34215"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34215\/revisions"}],"predecessor-version":[{"id":36681,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34215\/revisions\/36681"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=34215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=34215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=34215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}