{"id":34481,"date":"2022-03-06T23:03:54","date_gmt":"2022-03-06T23:03:54","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=34481"},"modified":"2022-03-06T23:03:54","modified_gmt":"2022-03-06T23:03:54","slug":"evaluating-case-diagnostic-criteria-for-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/evaluating-case-diagnostic-criteria-for-me-cfs\/","title":{"rendered":"Evaluating case diagnostic criteria for ME\/CFS"},"content":{"rendered":"<p><a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/09638288.2022.2043462\" target=\"_blank\" rel=\"noopener\">Evaluating case diagnostic criteria for myalgic encephalomyelitis\/ chronic fatigue syndrome (ME\/CFS): toward an empirical case definition<\/a>, by Karl E Conroy, Mohammed F Islam, Leonard A Jason <span style=\"text-decoration: underline;\">in<\/span>\u00a0<em>Disability and Rehabilitation,\u00a0<\/em>Mar 2, p 1-8 2022 [doi.org\/10.1080\/09638288.2022.2043462]<\/p>\n<p>&nbsp;<\/p>\n<h3><strong>Implications for rehabilitation<\/strong><\/h3>\n<ul>\n<li>ME\/CFS is a chronic illness with no consensus regarding case diagnostic criteria, which creates difficulty for patients seeking assistance and disability benefits.<\/li>\n<li>The current study compared three commonly used case definitions for ME\/CFS by factor analyzing symptomological data from an international sample of patients.<\/li>\n<li>Our results suggest three primary and four secondary symptom domains which differed from all three case definitions.<\/li>\n<li>These findings could help reduce barriers to care for those disabled with ME\/CFS by guiding the development of an empirically-based case definition.<\/li>\n<\/ul>\n<h3><strong>Abstract:<\/strong><\/h3>\n<p><strong>Purpose<\/strong><\/p>\n<p><img data-recalc-dims=\"1\" decoding=\"async\" class=\"alignright wp-image-34485 size-medium lazyload\" data-src=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/03\/Canadian-cover.jpg?resize=232%2C300&#038;ssl=1\" alt=\"\" width=\"232\" height=\"300\" data-srcset=\"https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/03\/Canadian-cover.jpg?resize=232%2C300&amp;ssl=1 232w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/03\/Canadian-cover.jpg?resize=116%2C150&amp;ssl=1 116w, https:\/\/i0.wp.com\/wames.org.uk\/cms-english\/wp-content\/uploads\/2022\/03\/Canadian-cover.jpg?w=467&amp;ssl=1 467w\" data-sizes=\"(max-width: 232px) 100vw, 232px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 232px; --smush-placeholder-aspect-ratio: 232\/300;\" \/>Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) is an illness characterized by a variety of symptoms including post-exertional malaise, unrefreshing sleep, and cognitive impairment. A variety of case definitions (e.g., the <a href=\"http:\/\/sacfs.asn.au\/download\/consensus_overview_me_cfs.pdf\" target=\"_blank\" rel=\"noopener\">Canadian Consensus Criteria<\/a> (CCC), the <a href=\"https:\/\/www.elevatedereham.co.uk\/information\/me-and-cfs-definitions\/international-consensus-criteria-for-myalgic-encephalomyelitis\/\" target=\"_blank\" rel=\"noopener\">Myalgic Encephalomyelitis International Consensus Criteria<\/a> (ME-ICC), and the<a href=\"https:\/\/www.cdc.gov\/me-cfs\/healthcare-providers\/diagnosis\/iom-2015-diagnostic-criteria.html\" target=\"_blank\" rel=\"noopener\"> Institute of Medicine<\/a> (IOM) criteria) have been used to diagnose patients. However, these case definitions are consensus-based rather than <a href=\"https:\/\/dictionary.cambridge.org\/dictionary\/english\/empirical\" target=\"_blank\" rel=\"noopener\">empirical<\/a>.<\/p>\n<p><strong>Materials and methods<\/strong><\/p>\n<p>The aim of the current study was to evaluate the validity of the aforementioned case definitions by factor analyzing a large, international sample (N = 2308) of ME\/CFS symptom data. We performed primary and secondary exploratory factor analyses on the <a href=\"https:\/\/csh.depaul.edu\/about\/centers-and-institutes\/ccr\/myalgic-encephalomyelitis-cfs\/Documents\/DEPAUL%20SYMPTOM%20QUESTIONNAIRE%20with%20SF-36%20and%20MFI%20and%20SI%205-18-11.pdf\" target=\"_blank\" rel=\"noopener\">DePaul Symptom Questionnaire<\/a>&#8216;s 54-item symptom inventory. These results were compared to the CCC, the ME-ICC, and the IOM criteria.<\/p>\n<p><strong>Results<\/strong><\/p>\n<p>We identified seven symptom domains, including post-exertional malaise, cognitive dysfunction, and sleep dysfunction. Contrary to many existing case criteria, our analyses did not identify pain as an independent factor.<\/p>\n<p><strong>Conclusions<\/strong><\/p>\n<p>Although our results implicate a <a href=\"https:\/\/www.statisticssolutions.com\/free-resources\/directory-of-statistical-analyses\/factor-analysis\/\" target=\"_blank\" rel=\"noopener\">factor solution<\/a> that best supports the CCC, revisions to the criteria are recommended.<\/p>\n<p><strong>Full paper behind paywall<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Evaluating case diagnostic criteria for myalgic encephalomyelitis\/ chronic fatigue syndrome (ME\/CFS): toward an empirical case definition, by Karl E Conroy, Mohammed F Islam, Leonard A Jason in\u00a0Disability and Rehabilitation,\u00a0Mar 2, p 1-8 2022 [doi.org\/10.1080\/09638288.2022.2043462] &nbsp; Implications for rehabilitation ME\/CFS is &hellip; <a href=\"https:\/\/wames.org.uk\/cms-english\/evaluating-case-diagnostic-criteria-for-me-cfs\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[2388,898,107,757,778,6489,6008,2241],"class_list":["post-34481","post","type-post","status-publish","format-standard","hentry","category-news","tag-canadian-consensus-criteria","tag-case-definitions","tag-diagnostic-criteria","tag-institute-of-medicine","tag-international-consensus-criteria","tag-karl-conroy","tag-mohammed-f-islam","tag-prof-leonard-jason"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-8Y9","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=34481"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34481\/revisions"}],"predecessor-version":[{"id":34487,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/34481\/revisions\/34487"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=34481"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=34481"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=34481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}