{"id":36657,"date":"2022-09-12T08:33:09","date_gmt":"2022-09-12T07:33:09","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=36657"},"modified":"2022-09-12T08:36:10","modified_gmt":"2022-09-12T07:36:10","slug":"understanding-me-and-long-covid","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/understanding-me-and-long-covid\/","title":{"rendered":"Understanding ME (and Long COVID)"},"content":{"rendered":"

Understanding Myalgic Encephalomyelitis – Myalgic Encephalomyelitis and Long COVID have overlapping presentation<\/strong><\/h2>\n

 <\/p>\n

Dr Sonya Marshall-Gradisnik and Dr Natalie Eaton-Fitch from Griffith University, on the Gold Coast in Australia, say there is a significant overlap in symptoms and possibly the underlying processes in ME and LC. Lessons should be learned from understanding ME:<\/strong><\/h3>\n

An important research challenge is the lack of a validated biomarker, laboratory-based test, and animal model, likely attributed to inconsistency in protocols, such as cell isolation, sample type, and technique. These challenges provide important lessons for research of Long Covid.<\/p>\n

By developing interdisciplinary and consistent research protocols, the pathomechanism of ME\/CFS and Long Covid can be elucidated. The recent interest in the overlap that exists between ME\/CFS and Long Covid poses several questions, such as whether Long Covid predisposes a person to ME\/CFS, and whether an individual has Long Covid or ME\/CFS.<\/p>\n

Pathomechanism – the process by which a disease or illness occurs. [Wik<\/a>i]<\/p><\/blockquote>\n

Research into the etiology of ME\/CFS and Long Covid should simultaneously identify the mechanism and diagnostic approach to both. ME\/CFS poses a substantial health concern and has recently been taken more seriously since the emergence of Long Covid, and renewed focus on diagnostic, research, and treatment practices is needed.<\/p>\n

\"\"

Proposed mechanisms underlying ME\/CFS<\/p><\/div>\n

Proposed mechanisms underlying ME\/CFS<\/strong><\/h3>\n

Myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) presents as a range of symptoms that affect multiple organ systems. Enteric dysbiosis, neurological and immune dysfunction, as well as impaired mitochondrial function are implicated in the pathomechanism of ME\/CFS. These symptoms also occur in Long Covid, although with differing prevalence.<\/p>\n

Read more about the nature of ME\/CFS:<\/strong><\/h3>\n

Understanding myalgic encephalomyelitis – Myalgic encephalomyelitis and Long Covid have overlapping presentation<\/a>, by Sonya Marshall-Gradisnik and Natalie Eaton-Fitch in<\/span> Science<\/em> Vol 377, Issue 6611 pp. 1150-1151, 8 Sep 2022 [DOI: 10.1126\/science.abo1261]<\/p>\n

The authors:<\/strong><\/h3>\n

Professor Sonya Marshall-Gradisnik<\/a> \u00a0 Dr Natalie Eaton-Fitch<\/a> \u00a0\u00a0 more research<\/a><\/p>\n

Comments:<\/strong><\/h3>\n

Medscape<\/strong>: Post-COVID Fatigue, Exercise Intolerance Signal ME\/CFS<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Understanding Myalgic Encephalomyelitis – Myalgic Encephalomyelitis and Long COVID have overlapping presentation   Dr Sonya Marshall-Gradisnik and Dr Natalie Eaton-Fitch from Griffith University, on the Gold Coast in Australia, say there is a significant overlap in symptoms and possibly the … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[1249,6196,5376,6154],"class_list":["post-36657","post","type-post","status-publish","format-standard","hentry","category-news","tag-dr-sonya-marshall-gradisnik","tag-long-covid","tag-natalie-eaton-fitch","tag-pathomechanism"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-9xf","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36657","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=36657"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36657\/revisions"}],"predecessor-version":[{"id":36665,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36657\/revisions\/36665"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=36657"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=36657"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=36657"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}