{"id":36717,"date":"2022-08-31T16:41:00","date_gmt":"2022-08-31T15:41:00","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=36717"},"modified":"2022-09-15T17:25:10","modified_gmt":"2022-09-15T16:25:10","slug":"research-long-covid-me-cfs-symptom-severity-in-germany","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/research-long-covid-me-cfs-symptom-severity-in-germany\/","title":{"rendered":"Research: Long COVID, ME\/CFS & symptom severity in Germany"},"content":{"rendered":"

Post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity<\/strong><\/h2>\n

 <\/p>\n

German researchers compared ME\/CFS and long COVID patients and found even mild C-19 can lead to PEM. Almost half of the LC patients met the criteria for ME\/CFS. The other half had a similar but less severe reaction to exertion, but the physiological changes in LC and ME\/CFS immune system functioning were found to be different.<\/p>\n

A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity<\/a>, by C Kedor, H Freitag, L Meyer-Arndt, K Wittke, LG Hanitsch, T Zoller, F Steinbeis, M Haffke, G. Rudolf, B Heidecker, T Bobbert, J Spranger, HD Volk, C Skurk, F Konietschke,
\nF Paul, U Behrends, J Bellmann-Strobl & C Scheibenbogen , in<\/span> Nature Communications<\/em> vol 13, no. 5104 (2022), 30 August 2022<\/p>\n

Research abstract:<\/strong><\/p>\n

\"\"A subset of patients has long-lasting symptoms after mild to moderate Coronavirus disease 2019 (COVID-19). In a prospective observational cohort study<\/a>, we analyze clinical and laboratory parameters in 42 post-COVID-19 syndrome patients (29 female\/13 male, median age 36.5 years) with persistent moderate to severe fatigue and exertion intolerance six months following COVID-19. Further we evaluate an age- and sex-matched postinfectious non-COVID-19 myalgic encephalomyelitis\/chronic fatigue syndrome cohort comparatively.<\/p>\n

Most post-COVID-19 syndrome patients are moderately to severely impaired in daily live. 19 post-COVID-19 syndrome patients fulfill the 2003 Canadian Consensus Criteria<\/a> for myalgic encephalomyelitis\/chronic fatigue syndrome.<\/p>\n

Disease severity and symptom burden is similar in post-COVID-19 syndrome\/ myalgic encephalomyelitis\/ chronic fatigue syndrome and non-COVID-19\/ myalgic encephalomyelitis\/ chronic fatigue syndrome patients.<\/p>\n

Hand grip strength is diminished in most patients compared to normal values in healthy. Association of hand grip strength with hemoglobin, interleukin 8 and C-reactive protein in post-COVID-19 syndrome\/non-myalgic encephalomyelitis\/chronic fatigue syndrome and with hemoglobin, N-terminal prohormone of brain natriuretic peptide, bilirubin, and ferritin in post-COVID-19 syndrome\/myalgic encephalomyelitis\/chronic fatigue syndrome may indicate low level inflammation<\/a> and hypoperfusion<\/a> as potential pathomechanisms.<\/p>\n

Comment:<\/strong><\/h3>\n

Laboratory Equipment<\/strong>:\u00a0Scientists link mild COVID-19 to CFS<\/a><\/p>\n

Newswise<\/strong>:\u00a0SARS Cov-2 can trigger Chronic Fatigue Syndrome<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity   German researchers compared ME\/CFS and long COVID patients and found even mild C-19 can lead to PEM. Almost half of the LC … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[2388,4267,5684,7122,447,6196,5692,7354],"class_list":["post-36717","post","type-post","status-publish","format-standard","hentry","category-news","tag-canadian-consensus-criteria","tag-carmen-scheibenbogen","tag-covid-19","tag-hypoperfusion","tag-inflammation","tag-long-covid","tag-maximal-handgrip-strength","tag-prospective-observational-cohort-study"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-9yd","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=36717"}],"version-history":[{"count":1,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36717\/revisions"}],"predecessor-version":[{"id":36718,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/36717\/revisions\/36718"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=36717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=36717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=36717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}