{"id":38844,"date":"2023-04-26T08:10:45","date_gmt":"2023-04-26T07:10:45","guid":{"rendered":"https:\/\/wames.org.uk\/cms-english\/?p=38844"},"modified":"2023-04-26T08:10:45","modified_gmt":"2023-04-26T07:10:45","slug":"research-post-exercise-fatigue-and-function-in-men-women-with-me-cfs","status":"publish","type":"post","link":"https:\/\/wames.org.uk\/cms-english\/research-post-exercise-fatigue-and-function-in-men-women-with-me-cfs\/","title":{"rendered":"Research: Post-exercise fatigue and function in men & women with ME\/CFS"},"content":{"rendered":"

This US pilot study was surprised to find that a six-minute walk test<\/a> didn’t produce as many post-exercise abnormalities in people with ME\/CFS and no major differences between men and women.<\/p>\n

\"\"Healthy people’s hearts returned to a slow rate in the 7 days after the walk tests, whereas the ME\/CFS group showed no significant change.<\/p>\n

It is uncertain how much physical exercise over how many days is required to sustain PEM<\/a>. The researchers suggest that a 12-min walk test<\/a> with instructions to \u201cwalk as fast as you can\u201d would be produce more results and would enable many disabled ME\/CFS patients, who lack mobility to participate in research from home.<\/p>\n

 <\/p>\n

Sex differences in post-exercise fatigue and function in myalgic encephalomyelitis\/chronic fatigue syndrome<\/a>, by Fred Friedberg, Jenna L Adamowicz, Patricia Bruckenthal, Maria Milazzo, Sameera Ramjan, Xiaoyue Zhang & Jie Yang in<\/span> Scientific Reports<\/em> vol 13, no: 5442, 3 Apr 2023<\/p>\n

Research abstract:<\/strong><\/p>\n

To assess biobehavioral sex differences in myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS) utilizing a low burden exercise protocol, 22 females and 15 males with ME\/CFS and 14 healthy controls underwent two six-min walk tests.<\/p>\n

Fifteen daily assessments were scheduled for fatigue and function ratings and heart monitoring. Six-min walk tests<\/a> were conducted on days 8 and 9. The ME\/CFS group showed high self-report fatigue and impaired physical function, whereas healthy controls did not show fatigue or function abnormalities.<\/p>\n

In patients, no significant post-exercise changes were found for heart rate variability (HRV); however, heart rate decreased in ME\/CFS males from Day 14 to Day 15 (p\u2009=\u20090.046). Female patients showed increased fatigue (p\u2009=\u20090.006) after the initial walk test, but a downward slope (p\u2009=\u20090.008) in fatigue following the second walk test. Male patients showed a decrease in self-report work limitation in the days after exercise (p\u2009=\u20090.046). The healthy control group evidenced a decrease in HRV after the walk tests from Day 9\u201314 (p\u2009=\u20090.038).<\/p>\n

This pilot study did not confirm hypotheses that females as compared to males would show slower exercise recovery on autonomic or self-report (e.g. fatigue) measures. A more exertion-sensitive test may be required to document prolonged post-exertional abnormalities in ME\/CFS.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

This US pilot study was surprised to find that a six-minute walk test didn’t produce as many post-exercise abnormalities in people with ME\/CFS and no major differences between men and women. Healthy people’s hearts returned to a slow rate in … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[7532,7531,2347,7526,7527,7524,7529,7528,584,585,7530,7525],"class_list":["post-38844","post","type-post","status-publish","format-standard","hentry","category-news","tag-12-minute-walk-test","tag-6-minute-walk-test","tag-dr-fred-friedberg","tag-jenna-l","tag-jenna-l-adamowicz","tag-jie-yang","tag-maria-milazzo","tag-patricia-bruckenthal","tag-pem","tag-post-exertional-malaise","tag-sameera-ramjan","tag-xiaoyue-zhang"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p5qkYK-a6w","_links":{"self":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/38844","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/comments?post=38844"}],"version-history":[{"count":4,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/38844\/revisions"}],"predecessor-version":[{"id":39004,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/posts\/38844\/revisions\/39004"}],"wp:attachment":[{"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/media?parent=38844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/categories?post=38844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wames.org.uk\/cms-english\/wp-json\/wp\/v2\/tags?post=38844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}