Tag Archives: cytokines
Increased 5-HT autoimmune activity in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons while bacterial translocation may drive autoimmune responses. This study has … Continue reading
Fatigue associated with daily cytokine fluctuations
Abstract Background Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not alleviated by rest. The lack of a clearly identified underlying mechanism has hindered the development of effective treatments. Studies have demonstrated elevated levels … Continue reading
Monitoring cytokines
Cytokines have been identified as playing a key role in the dysfunction found in ME. Abstract Serum and intracytoplasmic cytokines are mandatory in host defense against microbes, but also play a pivotal role in the pathogenesis of autoimmune diseases by … Continue reading
Low brain activity in CFS
Patients with chronic fatigue syndrome (CFS) had significantly less activation of the basal ganglia in response to a known stimulus compared with a control group, American researchers report. Brain imaging during a simulated reward task showed reduced activation in the … Continue reading
