Researchers from Dundee have found evidence that ME/CFS is associated with cardiovascular symptoms including autonomic dysfunction, impaired blood pressure regulation, and loss of beat-to-beat heart rate control. In addition they believe that a number of recent studies that report raised levels of oxidative stress low-grade inflammation and increased arterial stiffness contribute to a picture of increased cardiovascular risk in ME/CFS.
Their findings provide direct evidence of endothelial dysfunction in both the large and small vessels of patients with ME/CFS, which may warrant a large prospective trial of cardiovascular outcomes in the disease.
