A team led by Prof Basant Puri has used high resolution MRI scanning to uncover reduced grey matter volume in several parts of the brain. They believe that the data supports the hypothesis that significant neuroanatomical changes occur in CFS, and are consistent with the complaint of impaired memory that is common in this illness; they also suggest that subtle abnormalities in visual processing, and discrepancies between intended actions and consequent movements, may occur in CFS.
