Tag Archives: case definitions

Neuro-inflammatory and oxidative fatigue (NIOF) – new case definition of ME

Posted on 10/21/2015 by wames

Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) or Myalgic Encephalomyelitis (ME) is characterized by neuro-psychiatric (e.g. depression, irritability, sleep disorders, autonomic symptoms and neurocognitive defects) and physio-somatic (fatigue, a flu-like malaise, hyperalgesia, irritable bowel, muscle pain and tension) symptoms. New … Continue reading →

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The need to list exclusionary illnesses for SEID

Posted on 06/30/2015 by wames

Research abstract: The Institute of Medicine recently proposed a new case definition for chronic fatigue syndrome (CFS), as well as a new name, Systemic Exertion Intolerance Disease (SEID). Contrary to the Fukuda et al.’s CFS case definition, there are few … Continue reading →

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Diagnostic methods for ME/CFS: a review

Posted on 06/27/2015 by wames

Research abstract: Background: The diagnosis of myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is based on clinical criteria, yet there has been no consensus regarding which set of criteria best identifies patients with the condition. The Institute of Medicine has recently … Continue reading →

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Variability in symptoms complicates usefulness of case definitions

Posted on 06/03/2015 by wames

Research abstract: Background: Ambiguities in case definitions have created difficulties in replicating findings and estimating the prevalence rates for chronic fatigue syndrome (CFS) and Myalgic Encephalomyelitis (ME). Purpose: The current study examined differences in occurrence rates for CFS and ME … Continue reading →

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The essential features of ME & CFS need to be defined

Posted on 05/19/2015 by wames

Research abstract: Considerable debate surrounds the search for the defining features of patients with myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). Current case definitions were created through clinical consensus. Failure to operationalize these case definitions has led to considerable … Continue reading →

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Comparison of consensus & empirical ME/CFS definitions & criteria

Posted on 04/01/2015 by wames

Research abstract: Background:  Since the publication of the CFS case definition [Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue  syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121:953-959], there … Continue reading →

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Should those with lifelong fatigue be excluded from a diagnosis of ME?

Posted on 02/05/2015 by wames

Research abstract: The case definitions for chronic fatigue syndrome (CFS) and chronic fatigue syndrome/Myalgic Encephalomyelitis (ME) stipulate that the experience of lifelong fatigue is an exclusionary criterion (Carruthers et al., 2003 ; Fukuda et al., 1994 ). This article examines … Continue reading →

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More severe symptoms & impairment in ME than in CFS confirmed

Posted on 02/04/2015 by wames

Research abstract A revised sudden onset case definition for Myalgic Encephalomyelitis (ME) has been developed (Jason, Damrongvachiraphan, etal., 2012) based on past case definitions. In a prior study, Jason, Brown, and colleagues (2012 ) compared patients recruited using the 1994 … Continue reading →

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Defining ME/CFS: McGrath comments on Brown/Jason research

Posted on 09/12/2014 by wames

Simon McGrath at Phoenix rising comments on the full text (not available free) of Brown and Jason’s paper Validating a measure of myalgic encephalomyelitis/chronic fatigue syndrome symptomatology Extract from : Validating a measure of ME/CFS symptomatology – Brown & Jason … Continue reading →

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A definition of recovery in ME & CFS should be based on objective measures

Posted on 06/26/2014 by wames

Abstract   INTRODUCTION: Adamowicz and colleagues recently proposed to use “a consistent definition of recovery that captures a broad-based return to health with assessments of both fatigue and function as well as the patients’ perceptions of his/her recovery status” for patients with chronic … Continue reading →

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