Tag Archives: Neuroinflammation

Glial cell inhibitors: the next sleep drugs for FM and ME/CFS?

Health Rising blog post, by Cort Johnson, 15 September: Glial Cell Inhibitors: The Next Sleep Drugs for Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?   Glia: The Forgotten Brain Cell Sleep disturbances and severe stress as glial activators: key targets for … Continue reading

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Neuro inflammatory etiopathology of ME/CFS

Article abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating multi-systemic chronic illness of unknown etiology, classified as a neurological disorder by the World Health Organization (WHO). The symptomatology of the condition appears to emanate from a variety of sources … Continue reading

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PINCHED – Neuron Protein Marker studied in ME/CFS

Cort Johnson reports on The Role of PINCH in Chronic Energy Deficit in the CNS. The National CFIDS Foundation PINCH study is a timely one given the interest in neuroinflammation in ME/CFS. Hopefully over the next year we’ll get a … Continue reading

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Viruses and cytokines in ME

Research abstract Myalgic encephalomyelitis (ME) is a polymorphic clinical entity. In some patients, chronic infection with Epstein–Barr virus (EBV), human herpesvirus 6 (HHV-6), and human herpesvirus 7 (HHV-7) is regarded as an important pathogenetic factor that contributes to chronic neuroinflammation. … Continue reading

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Brain scans detect neuroinflammation in CFS

Abstract Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disease characterized by chronic, profound, disabling, and unexplained fatigue. Although it is hypothesized that brain inflammation is involved in the pathophysiology of CFS/ME, there is no direct evidence of neuroinflammation in patients … Continue reading

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Cytokines and neuropathic pain

Abstract Cytokines and chemokines are proteins that coordinate the immune response throughout the body. The dysregulation of cytokines and chemokines is a central feature in the development of neuroinflammation, neurodegeneration, and demyelination both in the central and peripheral nervous systems … Continue reading

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