Tag Archives: tricarboxylic acid cycle
Research: Metabolomic evidence for peroxisomal dysfunction in ME/CFS
Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Research conclusion: Our findings provide the first metabolomic evidence of peroxisomal dysfunction, and are consistent with dysregulation of lipid remodeling and the tricarboxylic acid cycle. These findings, if validated … Continue reading →
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Tagged Aaron Cheng, Adam Price, Ayan Roy, biomarker, Bohyun Lee, Christopher R Brydges, cytidine-5′-diphosphocholine pathway, Dana March Palmer, Dinesh K Barupal, Dr Daniel Peterson, Dr Ian Lipkin, Dr Lucinda bateman, Dr Susan Levine, Dr Suzanne Vernon, metabolomics, peroxisome, Prof Anthony Komaroff, Prof Jose Montoya, Prof Oliver Fiehn, Shreyas Joshi, tricarboxylic acid cycle, Yuanzhi Yu
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Possible clinical diagnostic tool for CFS based on the ratios of metabolites in blood plasma
Research abstract: Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state characterized by exertional and severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, lasting at least 6 consecutive months. Its pathogenesis remains incompletely understood. Here, we performed comprehensive … Continue reading →
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Tagged biomarkers, metabolites, tricarboxylic acid cycle, urea cycle, Yasuyoshi Watanabe, Yosky Kataoka
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