Tag Archives: Prof Anthony Komaroff

Research: Different risk factors distinguish ME/CFS from severe fatigue

Severe Fatigue is not the same as ME/CFS   US researchers led by Prof Komaroff found that severe fatigue was much more common than ME/CFS in a large group of nurses and the triggers were different. There was an increased … Continue reading

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Research: Gut dysfunction found in ME/CFS

Gut bacteria could have answers for ME/CFS   Two separate US studies have found significant differences in the gut microbiomes of people with ME/CFS  compared to healthy people, although it was not possible to tell if they were a cause … Continue reading

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Research: Metabolomic evidence for peroxisomal dysfunction in ME/CFS

Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome   Research conclusion: Our findings provide the first metabolomic evidence of peroxisomal dysfunction, and are consistent with dysregulation of lipid remodeling and the tricarboxylic acid cycle. These findings, if validated … Continue reading

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Diagnostic test research: Orthostatic challenge causes the same responses in Long COVID & ME/CFS

Orthostatic challenge causes distinctive symptomatic, hemodynamic and cognitive responses in Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Suzanne D Vernon, Sherlyn Funk, Lucinda Bateman, Gregory J Stoddard, Sarah Hammer, Karen Sullivan, Jennifer Bell, Saeed Abbaszadeh, W Ian Lipkin, Anthony … Continue reading

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Research review: Redox imbalance links COVID-19 & ME/CFS

Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome, by Bindu D Paul, Marian D Lemle, Anthony L Komaroff, Solomon H Snyder in PNAS August 24,  2021 118 (34); [doi.org/10.1073/pnas.2024358118]   Review abstract: Although most patients recover from acute COVID-19, … Continue reading

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Viewpoint: ME/CFS: when suffering is multiplied

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: when suffering is multiplied, by Anthony L Komaroff in Healthcare 2021, 9(7), 919 [doi.org/10.3390/healthcare9070919] 20 July 2021 (This article belongs to the Special Issue ME/CFS – the Severely and Very Severely Affected)   Article abstract: Myalgic encephalomyelitis/chronic fatigue … Continue reading

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Insights from ME/CFS may help unravel the pathogenesis of post-acute COVID-19 syndrome

Insights from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome, by Anthony L Komaroff, W Ian Lipkin in Trends in Molecular Medicine, 7 June 2021 [doi.org/10.1016/j.molmed.2021.06.002]   Highlights: In some people, the aftermath of acute … Continue reading

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Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion & ME/CFS

Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS, by Milica Milivojevic, Xiaoyu Che, Lucinda Bateman, Aaron Cheng, Benjamin A Garcia, Mady Hornig, Manuel Huber, Nancy G Klimas,Bohyun Lee, Hyoungjoo Lee, Susan Levine, Jose G … Continue reading

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Solve M.E. announces launch of US ‘You+M.E. Registry’ & Biobank to transform the study of ME/CFS

Solve M.E. announces launch of You + M.E. Registry and Biobank to transform the study of ME/CFS and post-viral, chronic illnesses likely impacted by COVID-19   New disease registry brings big data revolution to disease affecting nearly 20 million people … Continue reading

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Advances in understanding the pathophysiology of CFS

Advances in understanding the pathophysiology of Chronic Fatigue Syndrome, by Anthony L Komaroff in JAMA [Preprint July 5, 2019]   Viewpoint extracts: When does an illness become a disease? When the underlying biological abnormalities that cause the symptoms and signs of the … Continue reading

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