Category Archives: News

Association between cognitive performance & pain in CFS

Research abstract: BACKGROUND: In addition to the frequently reported pain complaints, performance-based cognitive capabilities in patients with chronic fatigue syndrome (CFS) with and without comorbid fibromyalgia (FM) are significantly worse than those of healthy controls. In various chronic pain populations, … Continue reading

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Do people with ME and CFS really recover?

The Recovery Question, by Dan Neuffer in Health Rising Forum, Sep 17 2015 There is much information out there on how to diagnose Fibromyalgia Syndrome (FMS) or Chronic Fatigue Syndrome (CFS) (also described as Myalgic Encephalomyelitis or ME). And whilst … Continue reading

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Perfectionism & stress in CFS could be due to HPA dysregulation

Article Background: There is increasing evidence that Chronic Fatigue Syndrome (CFS) may reflect a dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis after a prolonged period of hyperactivity due to chronic stress/overload. We and others have hypothesized that chronic stress and subsequent … Continue reading

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Oxidative phosphorylation & lactic acid excretion are impaired in severe ME

Case study abstract: Background: In this study the muscle bioenergetic function in response to exercise in severe ME was explored to see if the underlying metabolic problem in ME, responsible for the severe difficulties with trivial exercise, and the severe loss … Continue reading

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Key issues for understanding ME, biological markers & diagnostic criteria

Review abstract: Myalgic Encephalomyelitis (ME) continues to cause significant morbidity worldwide with an estimated one million cases in the United States. Hurdles to establishing consensus to achieve accurate evaluation of patients with ME continue, fuelled by poor agreement about case definitions, … Continue reading

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Group CBT for CFS

Research abstract: BACKGROUND: Meta-analyses have been inconclusive about the efficacy of cognitive behaviour therapies (CBTs) delivered in groups of patients with chronic fatigue syndrome (CFS) due to a lack of adequate studies. METHODS: We conducted a pragmatic randomised controlled trial … Continue reading

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Mitochondrial myopathy – differential diagnosis for ME

Research abstract: Introduction: Symptoms of mitochondrial diseases and chronic fatigue syndrome (CFS) frequently overlap and can easily be mistaken. Methods: We report the case of a patient diagnosed with CFS and during follow-up was finally diagnosed with mitochondrial myopathy by … Continue reading

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ACT (Acceptance and commitment therapy) for CFS

Research abstract: Acceptance is understood to be an important element in coping and  living with chronic illnesses such as diabetes and chronic pain, and increasing acceptance has been related to a number of positive  outcomes such as reduced symptoms as well … Continue reading

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Patients’ opinions of activity pacing

Research abstract: Objective: Despite the frequent recommendation of activity pacing as a coping strategy for patients with chronic pain and/or fatigue, pacing is interpreted in different ways and there is an absence of a widely accepted pacing scale. We have … Continue reading

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Patients’ ME research priorities

Research abstract: Background: The aim of this work was to involve patients in setting future priorities for myalgic encephalomyelitis (M.E.) research. Methods: A national on-line survey was developed collecting structured and unstructured data. Respondents were asked what they considered Action … Continue reading

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