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Is CFS an inflammatory disorder?
Review abstract: Background: Chronically elevated inflammation provides a putative target in the search of a meaningful biomarker for chronic fatigue syndrome (CFS). While research has investigated levels of inflammatory biomarkers in people with CFS compared with healthy controls, these groups have not yet … Continue reading
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Tagged Anthony J. Cleare, inflammatory disorder, R Strawbridge
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FM and CFS: underlying biology
Article abstract: There is an increasing interest in understanding the biological mechanism underpinning fibromyalgia (FM) and chronic fatigue syndrome (CFS). Despite the presence of mixed findings in this area, a few biological systems have been consistently involved, and the increasing number … Continue reading
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Tagged chronic fatigue, cortisol, Fibromyalgia, FM, hypothalamic-pituitary-adrenal axis, inflammatory disorder, mitochondrial dysfunction, neuroendocrine system, oxidative stress pathways
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Could toll-like receptors be a new therapeutic approach for ME?
Article abstract Perturbations in immune processes play an important role in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), a multifactorial disorder mainly characterized by severe and prolonged fatigue and typically affecting a variety of bodily systems including the immune system. Recent reports … Continue reading
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Tagged autonomic dysfunction, cytokines, Gut microbes, immunomodulators, inflammatory disorder, TLRs, toll-like receptors
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Probiotic B infantis improves immune system in CFS
Research abstract: Certain therapeutic microbes, including Bifidobacteria infantis (B. infantis) 35624 exert beneficial immunoregulatory effects by mimicking commensal-immune interactions; however, the value of these effects in patients with non-gastrointestinal inflammatory conditions remains unclear. In this study, we assessed the impact … Continue reading
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Tagged B. infantis 35624, gut, immune system, inflammatory disorder
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Cytokine flucutations reflect fluctutations in fatigue severity
Research Abstract Background: Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not alleviated by rest. The lack of a clearly identified underlying mechanism has hindered the development of effective treatments. Studies have demonstrated elevated … Continue reading
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Tagged cytokines, fatigue, inflammatory disorder, Jose G Montoya
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Inflammation in ME/CFS greater than in depression
A research trial by a multi-national team compared bio-markers in people with ME/CFS, depression and healthy people. Background: Depression is an inflammatory disorder while many authors declare myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) to be a functional disorder. The aim of … Continue reading
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Tagged bi-markers, cell-mediated immune response, depression, Frank Twisk, inflammatory disorder, Karl Ringel, Michael Maes, PICs, proinflammatory cytokines
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