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A possible bio-marker for distinguishing inflammation in IBS
Research abstract: Background: Recent studies demonstrated low-grade inflammation in patients with irritable bowel syndrome (IBS). However, these studies have been relatively small and do not enable examination of this factor in different subtypes of IBS and the possibility of confounding … Continue reading
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Tagged C-reactive protein, CRP, IBS, inflammation, Irritable bowel syndrome, subgroups
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Video presentation of Alan Light’s gene expression research
“Using Gene Expression to Objectively Subset & Diagnose FM, CFS and Depression” Published on Dec 18, 2014 Alan Light, PhD gave this presentation during OFFER’s 2014 Healthcare Provider Conference. In this study, they looked at 46 genes [using the leukocytes] … Continue reading
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Tagged Alan R Light, diagnosis, gene expression, subgroups
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Serum cytokine levels vary in moderate and severe CFS/ME patients
Volume 70, Issue 1, November 2014, Pages 45 Research aims Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness with an unknown aetiology and diagnosis is based on symptom-specific criteria. Immunological dysregulation and cytokine abnormalities are consistent in CFS/ME. As … Continue reading
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Tagged serum cytokines, severe ME, subgroups
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Severity scales in CFS/ME
Research abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a physical and cognitive disabling illness, characterised by severe fatigue and a range of physiological symptoms that primarily affects women. The immense variation in clinical presentation suggests differences in severity based on … Continue reading
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Tagged Dr Sonya Marshall-Gradisnik, severity scales, subgroups
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Neuropsychological impairment in women with CFS
Abstract This study examines neuropsychological impairments associated with chronic fatigue syndrome (CFS) and explores their association with related clinical factors. Sixty-eight women with CFS were assessed with a neuropsychological battery. Raw scores were adjusted for age and gender and were … Continue reading
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Tagged cognitive dysfunction, female, neuropsychological impairments, subgroups, women
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Natural killer cells in severe CFS
Abstract Maintenance of health and physiological homeostasis is a synergistic process involving tight regulation of proteins, transcription factors and other molecular processes. The immune system consists of innate and adaptive immune cells that are required to sustain immunity. The presence … Continue reading
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Tagged immune dysfunction, Natural Killer cells, NK cells, severe ME, subgroups
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Review of biomarkers in CFS
Abstract Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis, and diagnosis. Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more … Continue reading
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Tagged biomarkers, phenotypes, Prof Leonard Jason, subgroups
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Important to distinguish ME (with Post-exertional malaise) from CFS
Abstract Myalgic Encephalomyelitis (ME) was identified as a new clinical entity in 1959 and has been acknowledged as a disease of the central nervous system/neurological disease by the World Health Organisation since 1969. Cognitive impairment, (muscle) weakness, circulatory disturbances, marked … Continue reading
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Tagged diagnosis, Frank Twisk, immune system, PEM, Post-exertional malaise, subgroups, terminology
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Videos by ME experts online
Dutch patient group ME/cvs Vereniging has hosted 30+ 3-10 minute talks about various aspects of ME on their Youtube page. Speakers include: Dr Nigel Speight (WAMES advisor); Prof Dr Kenny Meirleir; Prof Dr FC Visser; Dr Meinte Vollema, Dr Charles … Continue reading
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Tagged children, Dr Charles Shepherd, Dr Meinte Vollema, Dr Nigel Speight, hormones, pain, POTS, Prof FC Visser, Prof Kenny Meirleir, sleep, subgroups
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Does the energy envelope theory improve function?
Abstract Objective/Hypothesis: The objective of this study was to examine sub-types of individuals with chronic fatigue syndrome based on variables that are associated with the energy envelope theory and to examine the role of coping strategies in explaining the differences … Continue reading
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Tagged AA Brown, energy envelope theory, energy management, Leonard Jason, MA Evans, pacing, subgroups
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