Tag Archives: Trudy Chalder

Design of PACE trial

Abstract: Background: Clinical trials require large monetary and time commitments and should provide information on both whether and how treatments work. Treatment mechanisms can be studied using mediation analysis, allowing refinement of treatments. Mediation studies often use only single contemporaneous measures of mediator and … Continue reading

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CFS patients want name to reflect physical symptoms

Research abstract: OBJECTIVE: Medically unexplained symptoms/syndromes are common, highly distressing and are often associated with profound disability. One of the controversies surrounding this area relates to which umbrella term should be used to group such symptoms. The purpose of this … Continue reading

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Recovery rates from CFS following CBT

Research Abstract Highlights This study investigates recovery from CFS in a routine practice. Approximately 18% of people with CFS recover after CBT. The study of CBT in routine practice demonstrated recovery rates akin to RCTs. Cognitive behavioural therapy (CBT) is … Continue reading

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Childhood stressors in the development of CFS and FM

Review Abstract Background Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are both highly prevalent conditions associated with extreme disability and with the development of co-morbid psychiatric disorders, such as depression and anxiety. Childhood stressors have been shown to induce persistent … Continue reading

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