Category Archives: News

Macrophagic myofasciitis, vaccinations and CFS

Abstract Macrophagic myofasciitis (MMF) characterized by specific muscle lesions assessing long-term persistence of aluminium hydroxide within macrophages at the site of previous immunization has been reported with increasing frequency in the past 10 years. We describe clinical and laboratory findings … Continue reading

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Is CFS a meme (dysfunctional culturally-transmitted idea-infection)?

Response to 2004 article by Peter White: What causes Chronic Fatigue Syndrome? Is Chronic Fatigue Syndrome a meme?, by Anthony D Collings, David Newton in BMJ 18 June 2014 In his 1976 book ‘The Selfish Gene’ (1) Richard Dawkins coined … Continue reading

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Decreased basal ganglia function and relationship to fatigue in CFS

Abstract Reduced basal ganglia function has been associated with fatigue in neurologic disorders, as well as in patients exposed to chronic immune stimulation. Patients with chronic fatigue syndrome (CFS) have been shown to exhibit symptoms suggestive of decreased basal ganglia … Continue reading

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Reduced blood flow following reduced nitrergic nitric oxide in POTS

Abstract Cognitive deficits are characteristic of postural tachycardia syndrome (POTS). Intact nitrergic nitric oxide (NO) is important to cerebral blood flow (CBF) regulation, to neurovascular coupling, and to cognitive efficacy. POTS patients often experience defective (NO) mediated vasodilation caused by … Continue reading

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Cerebrospinal fluid pressure may be problem in CFS

Abstract   Objective Unsuspected idiopathic intracranial hypertension (IIH) is found in a significant minority of patients attending clinics with named headache syndromes, if it is specifically sought out. Chronic fatigue syndrome is frequently associated with headache. Could the same be … Continue reading

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ME/CFS brain and tissue bank protocol

Abstract (provisional)   Background Our aim, having previously investigated through a qualitative study involving extensive discussions with experts and patients the issues involved in establishing and maintaining a disease specific brain and tissue bank for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), … Continue reading

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Why those with treatable diseases get more sympathy than ME

Martha Gill, a blogger on politics and neurosciences comments: According to reports, a third of people who think they have ME may actually be suffering from something else – a disease called postural tachycardia syndrome (PoTS). It has the same symptoms … Continue reading

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POTS affects mostly young women

Abstract Objective To examine a large UK cohort of patients with postural tachycardia syndrome (PoTS), to compare demographic characteristics, symptoms and treatment of PoTS at one centre compared to the largest patient group PoTS UK and to verify if their … Continue reading

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Post-traumatic hypopituitarism (PTHP) often misdiagnosed as CFS

Patients misdiagnosed with CFS when they have brain damage Post-traumatic hypopituitarism (PTHP) is often cause by head injury Symptoms include depression, obesity, fatigue and chronic pain Numerous studies have shown that between 20 and 30 per cent of the 135,000 … Continue reading

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Blood flow increases in the brain in POTS

Abstract Decreased upright cerebral blood flow (CBF) with hyperpnea and hypocapnia is seen in a minority of patients with postural tachycardia syndrome (POTS). More often, CBF is not decreased despite upright neurocognitive dysfunction. This may result from time-dependent changes in … Continue reading

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