Tag Archives: Multidimensional Fatigue Inventory

A better way to measure ME/CFS experience is needed

Research abstract: PURPOSE: Debilitating fatigue is a core symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); however, the utility of patient-reported symptom outcome measures of fatigue for ME/CFS patients is problematic due to ceiling effects and issues with reliability and validity. … Continue reading

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Duloxetine – little effect on general fatigue but helps mental fatigue in CFS

Research abstract Objective: To assess the efficacy and safety of duloxetine in patients with chronic fatigue syndrome. Methods: A 12-week, randomized, double-blind study was designed to compare duloxetine 60-120 mg/day (n=30) with placebo (n=30) for efficacy and safety in the … Continue reading

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Decreased basal ganglia function and relationship to fatigue in CFS

Abstract Reduced basal ganglia function has been associated with fatigue in neurologic disorders, as well as in patients exposed to chronic immune stimulation. Patients with chronic fatigue syndrome (CFS) have been shown to exhibit symptoms suggestive of decreased basal ganglia … Continue reading

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Post-exertional symptom exacerbation follows mental effort in ME/CFS

Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, long-term condition characterised by extreme fatigue (worsened by exertion), muscle and joint pain, and sleep disturbance. Post-exertional fatigue has been demonstrated previously following physical exercise, but not from mental exertion … Continue reading

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