Category Archives: News

Homeostatic drive in Gulf War illness and CFS

Abstract A key component in the body’s stress response, the hypothalamic-pituitary-adrenal (HPA) axis orchestrates changes across a broad range of major biological systems. Its dysfunction has been associated with numerous chronic diseases including Gulf War Illness (GWI) and chronic fatigue … Continue reading

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Severity of infection leads to CFS in adolescents

Abstract This study focused on identifying risk factors for adolescent post-infectious chronic fatigue syndrome (CFS), utilizing a prospective, nested case–control longitudinal design in which over 300 teenagers with infectious mononucleosis (IM) [aka EBV or glandular fever] were identified through primary … Continue reading

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Prudent healthcare and ME

On 16th January 2014 the Health Minister introduced the principles of ‘Prudent healthcare’ which would shape future development of services in NHS Wales: Do no harm Undertake the minimum appropriate intervention Work in co-production with the patient, to consider “what … Continue reading

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Are ME and CFS different illnesses?

Abstract Considerable discussion has transpired regarding whether chronic fatigue syndrome is a distinct illness from Myalgic Encephalomyelitis. A prior study contrasted the Myalgic Encephalomyelitis International Consensus Criteria with the Fukuda and colleagues’ chronic fatigue syndrome criteria and found that the … Continue reading

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Case definition criteria for CFS and ME

Abstract BACKGROUND: Considerable controversy has transpired regarding the core features of myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). Current case definitions differ in the number and types of symptoms required. This ambiguity impedes the search for biological markers and … Continue reading

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Adolescents’ experiences of living with CFS

‘Sometimes it feels as if the world goes on without me’: adolescents’ experiences of living with chronic fatigue syndrome Abstract Aims and objectives: To explore the experience of being an adolescent with chronic fatigue syndrome. BACKGROUND Despite ample research, chronic … Continue reading

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Valacyclovir (antiviral) treatment of chronic fatigue in adolescents

Abstract Chronic fatigue syndrome (CFS) presents with fatigue, low motivation, diminished mood, and reduced activity, all symptoms having extensive diagnostic overlaps with depression. Studies have linked chronic viral infections with CFS, and antiviral therapy has effectively treated CFS in adult … Continue reading

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Multivitamin mineral supplementation helpful in CFS

Abstract Background Chronic fatigue syndrome (CFS) is characterized by medically unexplained persistent or reoccurring fatigue lasting at least 6 months. CFS has a multifactorial pathogenesis in which oxidative stress (OS) plays a prominent role. Treatment is with a vitamin and … Continue reading

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Experiences of daily activity in CFS/ME & implications for rehabilitation programmes

Abstract PURPOSE Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS/ME), has a significant impact upon daily functioning. Most recommended treatments aim to alter activity patterns based upon assumptions of activity avoidance. However, as there is limited research on the … Continue reading

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Low oxygen uptake by muscle cells causes exercise intolerance

Abstract Background The insufficient metabolic adaptation to exercise in Chronic Fatigue Syndrome (CFS) is still being debated and poorly understood. Methods We analysed the cardiopulmonary exercise tests of CFS patients, idiopathic chronic fatigue (CFI) patients and healthy visitors. Continuous non-invasive … Continue reading

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