Tag Archives: B cells

CD24 expression & B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS

CD24 expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome , by Fane K. Mensah, Christopher W Armstrong, Venkat Reddy, Amolak S Bansal, Saul Berkovitz, Maria Leandro … Continue reading

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Altered B cells found in whole blood gene expression in adolescent CFS

Research abstract Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival, by Chinh Bkrong Nguyen, Lene Alsøe, Jessica M. Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde … Continue reading

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CFS and the immune system

Review summary: Chronic fatigue syndrome and the immune system: Where are we now?, by Fane Kojo Fosu Mensaha, Amolak Singh Bansal, Brian Ford, Geraldine Cambridge in Neurophysiologie Clinique/Clinical Neurophysiology [Available online 12 April 2017] Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by multiple … Continue reading

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B-cell function in patients with ME/CFS

Research summary: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a  heterogeneous condition of unknown etiology characterized by multiple symptoms including fatigue, post-exertional malaise and cognitive impairment, lasting for at least 6 months. Recently, two clinical trials of B-cell depletion therapy with rituximab (anti-CD20) reported convincing … Continue reading

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B cells in the immune systems of people with CFS

Research abstract Limited immunological changes have been previously reported in B cell phenotype in Chronic Fatigue Syndrome (CFS) patients, so there is no clear established role of B cells in the pathophysiology of CFS patients. The aim of this study … Continue reading

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Epstein Barr virus following immune deficiency found in CFS subgroup

Abstract Epstein-Barr virus (EBV) has long been discussed as a possible cause or trigger of Chronic Fatigue Syndrome (CFS). In a subset of patients the disease starts with infectious mononucleosis and both enhanced and diminished EBV-specific antibody titers have been … Continue reading

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Rituximab UK trial update

Invest in ME have now raised £57,000 for their UK rituximab trial from a variety of organisations and individuals and can begin the first phase. The UCL team is working on a study to confirm and expand Dr Bansal’s B cell results … Continue reading

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