Tag Archives: autoimmune
Hope for an ME/CFS autoimmune subset: a German researcher steps forward
Simmaron Research blog post, by Cort Johnson, 1 April 2018: Hope for an ME/CFS Autoimmune Subset: A German Researcher Steps Forward German Researcher Steps Up Carmen Scheibenbogen MD is another sign that the ME/CFS field is slowly but surely hopefully … Continue reading
Immune exhaustion & new gut findings in ME/CFS
Tea-Time at Simmaron I: Mady Hornig on the “Peterson Subsets”, Immune Exhaustion and New Gut Findings In ME/CFS by Cort Johnson at simmaronresearch.com, September 28, 2015 The Simmaron Research Foundation is out to redefine ME/CFS scientifically. In an recent event called … Continue reading
Central nervous system clues found for cognitive dysfunction in CFS
Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome is an unexplained debilitating disorder that is frequently associated with cognitive and motor dysfunction. We analyzed cerebrospinal fluid from 32 cases, 40 subjects with multiple sclerosis and 19 normal subjects frequency-matched for age and … Continue reading
Is CFS an autoimmune disorder with vasoactive neuropeptide dysfunction?
Abstract Chronic fatigue syndrome is a disorder characterised by prolonged fatigue and debility and is mostly associated with post-infection sequelae although ongoing infection is unproven. Immunological aberration is likely and this may prove to be associated with an expanding group … Continue reading
Autoimmune basis for Postural Tachycardia Syndrome
Abstract BACKGROUND Patients with postural tachycardia syndrome (POTS) have exaggerated orthostatic tachycardia often following a viral illness, suggesting autoimmunity may play a pathophysiological role in POTS. We tested the hypothesis that they harbor functional autoantibodies to adrenergic receptors (AR). METHODS … Continue reading
Immune dysregulation in CFS similar to autoimmune disorders
Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading
Medications cause 70% of dry eyes, mouth etc. in CFS
Chronic fatigue syndrome (CFS) is a heterogeneous and multisystemic disorder of unknown pathogenesis and etiology. It is characterized by prolonged generalized and abnormal fatigue post-exercise (98%), recurrent headache (90%) and problems of concentration and memory (85%) that have lasted for … Continue reading
Increased 5-HT autoimmune activity in ME/CFS
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons while bacterial translocation may drive autoimmune responses. This study has … Continue reading
Monitoring cytokines
Cytokines have been identified as playing a key role in the dysfunction found in ME. Abstract Serum and intracytoplasmic cytokines are mandatory in host defense against microbes, but also play a pivotal role in the pathogenesis of autoimmune diseases by … Continue reading
