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Variable effects of clonidine treatment in CFS
Research abstract: Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Although catechol-O-methyltransferase (COMT) metabolizes catecholamines, main effectors of sympathetic function, COMT genetic variation effects on clonidine treatment are unknown. Chronic fatigue syndrome (CFS) is hypothesized … Continue reading
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Tagged catechol-O-methyltransferase, clonidine, COMT, KT Hall
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Clonidine has little effect on autonomic cardiovascular & orthostatic symptoms in adolescents with CFS
Research abstract: Background: Chronic Fatigue Syndrome (CFS) is a common and disabling condition in adolescence with few treatment options. A central feature of CFS is orthostatic intolerance and abnormal autonomic cardiovascular control characterized by sympathetic predominance. We hypothesized that symptoms … Continue reading
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Tagged abnormal autonomic cardiovascular control, adolescents, clonidine, NorCAPITAL project, Norway, orthostatic intolerance, teenagers, young people
Comments Off on Clonidine has little effect on autonomic cardiovascular & orthostatic symptoms in adolescents with CFS
Clonidine in the treatment of adolescent CFS: pilot study
Norwegian researchers have completed a trial into the use of Clonidine with adolescents with CFS. Clonidine is used for a wide range of disorders including hypertension, neuropathic pain, ADHD, anxiety/panic disorder, migraine and hot flushes. ABSTRACT: BACKGROUND: This pilot study … Continue reading
