Tag Archives: COMT

Pain, genes, drugs & you

Posted on April 25, 2018 by wames

Health rising blog post, by Cort Johnson, 20 April 2018: Pain, Genes, Drugs and You: How Your Genetic Makeup May Be Keeping You in Pain From Dr. Trescott’s lecture given to the Physician Partners of America: “Your Genes, Your Pain … Continue reading →

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Variable effects of clonidine treatment in CFS

Posted on July 29, 2016 by wames

Research abstract: Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Although catechol-O-methyltransferase (COMT) metabolizes catecholamines, main effectors of sympathetic function, COMT genetic variation effects on clonidine treatment are unknown. Chronic fatigue syndrome (CFS) is hypothesized … Continue reading →

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COMT gene dysfunction linked to susceptibility to infection in CFS

Posted on September 11, 2015 by wames

Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading →

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