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Latest News
- Sleep problems in adolescents with CFS: a case-control study nested within a prospective clinical cohort
- Review of the quality control checks performed by current genome-wide & targeted-genome association studies on ME/CFS
- Systematic review of the epidemiological burden of ME/CFS across Europe: current evidence & EUROMENE research recommendations for epidemiology
- Heart rate thresholds to limit activity in ME/CFS patients (pacing): comparison of heart rate formulae
- The feasibility & acceptability of an early intervention in primary care to prevent CFS in adults
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Tag Archives: COMT
Variable effects of clonidine treatment in CFS
Research abstract: Clonidine, an α2-adrenergic receptor agonist, decreases circulating norepinephrine and epinephrine, attenuating sympathetic activity. Although catechol-O-methyltransferase (COMT) metabolizes catecholamines, main effectors of sympathetic function, COMT genetic variation effects on clonidine treatment are unknown. Chronic fatigue syndrome (CFS) is hypothesized … Continue reading
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Tagged catechol-O-methyltransferase, clonidine, COMT, KT Hall
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COMT gene dysfunction linked to susceptibility to infection in CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading
Posted in News
Tagged COMT, HPA axis functioning, immune dysregulation, immunoglobulin, RRTI, upper respiratory tract infections
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