Tag Archives: mitochondrial dysfunction

Prof Garth Nicolson’s research: ME & restoring mitochondrial functioning

Posted on 07/06/2016 by wames

Prof. Garth Nicolson introduces his research: We have been involved in research on the role of mitochondrial function in ME/CFS for some time and have found that restoring inner mitochondrial membrane (IMM) trans-membrane potential is essential. When mitochondrial membrane lipids are damaged, the IMM becomes … Continue reading →

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A new approach for investigating mitochondrial DNA in ME

Posted on 06/23/2016 by wames

Research abstract: In mitochondrial research, many investigators have examined the association between mitochondrial DNA (mtDNA) variants in rare as well as common complex diseases. Previous studies at the CHM (NWU) detected three known pathogenic mtDNA variants (m.7497G>A, m.9185T>C and m.10197G>A) at … Continue reading →

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More in-depth mitochondrial testing in ME/CFS proposed

Posted on 06/22/2016 by wames

Blog post by Cort Johnson in Health Rising forum, 20 June 2016: Researchers Call For More In-depth Mitochondrial Testing in Chronic Fatigue Syndrome (ME/CFS) More Extensive Mitochondrial Testing Proposed A letter to the editor of the BioMed Central Journal urged … Continue reading →

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Prof Ron Davis’ severe ME study finds problems with energy metabolism

Posted on 06/10/2016 by wames

ME Action news article, by Simon McGrath, 4 June 2016: Ron Davis: Preliminary data shows problems with energy metabolism Professor Ron Davis presented new findings from his Big Data study at Friday’s Invest in ME 2016 conference. Davis’s preliminary data … Continue reading →

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Dr Robert Naviaux – the mitochondria man

Posted on 05/10/2016 by wames

Health rising blog article by Cort Johnson, 21 April: An Eye on “The Mitochondria Man” : Robert Naviaux and Chronic Fatigue Syndrome (ME/CFS)  This is the start of an “Eye On” series focusing on researchers new to the chronic fatigue … Continue reading →

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End ME/CFS Severe Patient Study Turns to the Mitochondria

Posted on 03/24/2016 by wames

Health rising article, by Cort Johnson 18 March 2016: End ME/CFS Severe Patient Study Turns to the Mitochondria The mantra at the Severely Ill/Big Data study at the Open Medicine Foundation is to follow the evidence where it leads. We … Continue reading →

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Dr Sarah Myhill interview: energy and mitochondrial function

Posted on 01/13/2016 by wames

Niki Gratrix interviews Dr Sarah Myhill, published on 6 Oct 2015 Covered in this interview from the Abundant Energy Summit: rebooting Mitochondrial Function and nutrient status for optimum energy.  Lasts 40 minutes with powerpoint slides.

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The many roads to mitochondrial dysfunction in neuroimmune & neuropsychiatric disorders

Posted on 08/28/2015 by wames

Research abstract: BACKGROUND Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial diseases. Examples of such illnesses include bipolar disorder, multiple sclerosis, Parkinson’s disease, schizophrenia, depression, autism, and chronic … Continue reading →

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Fatigue is prevalent and debilitating in patients with mitochondrial disease

Posted on 06/12/2015 by wames

Highlights Perceived fatigue is a prominent and often debilitating symptom in patients with mitochondrial disease. Perceived fatigue correlates with disease severity but not genotype. Excessive sleepiness is prevalent but dissociated with perceived fatigue in patients with mitochondrial disease. Perceived fatigue … Continue reading →

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FM and CFS: underlying biology

Posted on 04/23/2015 by wames

Article abstract: There is an increasing interest in understanding the biological mechanism underpinning fibromyalgia (FM) and chronic fatigue syndrome (CFS). Despite the presence of mixed findings in this area, a few biological systems have been consistently involved, and the increasing number … Continue reading →

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