Tag Archives: mitochondrial dysfunction

Metabolic dysfunction in ME/CFS not due to anti-mitochondrial antibodies

Metabolic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome not due to anti-mitochondrial antibodies, by Isabell Nilsson, Jeremy Palmer, Eirini Apostolou, Carl-Gerhard Gottfries, Muhammad Rizwan, Charlotte Dahle and Anders Rosén in Front. Med., 31 March 2020 [doi.org/10.3389/fmed.2020.00108 ]   Research abstract: Metabolic profiling … Continue reading

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Human Herpesvirus-6 reactivation, mitochondrial fragmentation, & the coordination of antiviral & metabolic phenotypes in ME/CFS

Human Herpesvirus-6 reactivation, mitochondrial fragmentation, and the coordination of antiviral and metabolic phenotypes in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, by Philipp Schreiner, Thomas Harrer, Carmen Scheibenbogen, Stephanie Lamer, Andreas Schlosser, Robert K Naviaux and Bhupesh K Prusty in ImmunoHorizons April … Continue reading

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The effect of ME/CFS severity on cellular bioenergetic function

The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function, by Cara Tomas, Joanna L Elson, Victoria Strassheim, Julia L Newton, Mark Walker in PLoS One vol 15, #4, e0231136, April 10, 2020   Research abstract: Myalgic … Continue reading

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Carnitine conjugation profiling in a selected cohort of patients with CFS

Carnitine conjugation profiling in a selected cohort of patients with CFS, by L Du Plessis. MSc BioChem Dissertation 2019, North West University, South Africa.  21648859   Research abstract: Chronic fatigue syndrome (CFS) is classified by the World Health Organisation (WHO) … Continue reading

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An isolated complex V inefficiency & dysregulated mitochondrial function in immortalized lymphocytes from ME/CFS patients

An isolated complex V inefficiency and dysregulated mitochondrial function in immortalized lymphocytes from ME/CFS patients, by Daniel Missailidis, Sarah J Annesley, Claire Y Allan, Oana Sanislav, Brett A Lidbury, Donald P Lewis and Paul R Fisher in J. Mol. Sci. … Continue reading

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MtDNA population variation in ME/CFS in two populations

MtDNA population variation in Myalgic encephalomyelitis/ Chronic fatigue syndrome in two populations: a study of mildly deleterious variants, by Marianne Venter, Cara Tomas, Ilse S Pienaar, Victoria Strassheim, Elardus Erasmus, Wan-Fai Ng, Neil Howell, Julia L Newton, Francois H Van … Continue reading

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Changes in the transcriptome of circulating immune cells of a N Z cohort with ME/CFS

Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome, by Eiren Sweetman, Margaret Ryan, Christina Edgar, Angus MacKay, Rosamund Vallings, Warren Tate in International Journal of Immunopathology and Pharmacology vol 33 2019 [Published … Continue reading

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A new approach to find biomarkers in CFS/ME by single-cell Raman micro-spectroscopy

A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy, by Jiabao Xu,  Michelle Potter,  Cara Tomas,  Jo Elson,  Karl Morten,  Joanna Poulton,  Ning Wang, Hanqing Jin,  Zhaoxu Hou and Wei Huang in Analyst 2018 [published 22Aug 2018] Research abstract: Chronic fatigue syndrome … Continue reading

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KPAX002 as a treatment for ME/CFS – disappointing trial results

  Research abstract: KPAX002 as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a prospective, randomized trial, by Jose G Montoya, Jill N Anderson, Danya L Adolphs, Lucinda Bateman, Nancy Klimas, Susan M Levine, Donn W Garvert, Jon D Kaiser … Continue reading

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Review of potential causes of muscle dysfunction in ME/CFS

Review abstract: Purpose of Review: Here, we review potential causes of muscle dysfunction seen in many patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) such as the effects of oxidative and nitrosative stress (O&NS) and mitochondrial impairments together with reduced heat … Continue reading

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