Monthly Archives: March 2014
CFS after swine flu
We report two cases of Chronic Fatigue Syndrome (CFS) after Swine Flu vaccination. CLINICAL BACKGROUND CASE ONE Mrs A was a 52 year old married lady of Caucasian background, working in a profession allied to medicine in a Devon hospital. … Continue reading
Health Minister video about prudent healthcare
Health and Social Services Minister Mark Drakeford talks about Prudent Healthcare in a Welsh Government video published on Mar 24, 2014. Read a summary of the principles of prudent healthcare
ME/CFS Task & Finish Group update
WAMES took part in the 2nd Welsh Government Task & Finish Group meeting for ME/CFS on 21st February. The Terms of Reference for the group were confirmed as: The Task and Finish Group will provide expert advice to the Welsh … Continue reading
Autoimmune basis for Postural Tachycardia Syndrome
Abstract BACKGROUND Patients with postural tachycardia syndrome (POTS) have exaggerated orthostatic tachycardia often following a viral illness, suggesting autoimmunity may play a pathophysiological role in POTS. We tested the hypothesis that they harbor functional autoantibodies to adrenergic receptors (AR). METHODS … Continue reading
WAMES AGM 1st April
The WAMES AGM will take place on 1st April in Dinas Powys. This will be a short business meeting to report on the activities of the past year and plan the priorities for the coming year. Contact Jan if you … Continue reading
The role of the HPA-axis in adolescent CFS
Abstract BACKGROUND: There is accumulating evidence of hypothalamic-pituitary-adrenal (HPA) axis hypofunction in chronic fatigue syndrome (CFS). However, knowledge of this hypofunction has so far come exclusively from research in adulthood, and its clinical significance remains unclear. The objective of the … Continue reading
Immune dysregulation in CFS similar to autoimmune disorders
Abstract Perturbations in immune processes are a hallmark of a number of autoimmune and inflammatory disorders. Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is an inflammatory disorder with possible autoimmune correlates, characterized by reduced NK cell activity, elevations in regulatory T cells … Continue reading
Immune dysfunction worse in severe CFS patients
Abstract Objective: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disabling illness, characterized by persistent, debilitating fatigue and a multitude of symptoms. Immunological alterations are prominent in CFS/ME cases, however little is known about the relationship between CFS/ME severity and the … Continue reading
Adverse effects of antidepressants greater than reported
Abstract Background In the context of rapidly increasing antidepressant (AD) use internationally, and recent reviews raising concerns about efficacy and adverse effects, this study aimed to survey the largest sample of AD recipients to date. Methods An online questionnaire about … Continue reading