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- Dysregulated provision of oxidisable substrates to the mitochondria in ME/CFS lymphoblasts
- Sex-based differences in plasma autoantibodies to CNS proteins in Gulf War veterans versus healthy & symptomatic controls
- Sick of the sick role: narratives of what ‘recovery’ means to people with CFS/ME
- Plasma proteomics publication shows disrupted cell-to-cell signaling in ME/CFS
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Tag Archives: immune dysfunction
Cytokine profiling of extracellular vesicles isolated from plasma in ME/CFS
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/ chronic fatigue syndrome: a pilot study, by Ludovic Giloteaux, Adam O’Neal, Jesús Castro-Marrero, Susan M Levine, Maureen R Hanson in J Transl Med. 2020 Oct 12;18(1):387 [doi: 10.1186/s12967-020-02560-0] Research … Continue reading
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Tagged Adam O'Neal, cytokines, Dr Susan Levine, extracellular vesicles, immune dysfunction, Jesús Castro-Marrero, Ludovic Giloteaux, Prof Maureen Hanson
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Modification of immunological parameters, oxidative stress markers, mood symptoms, & well-being status in CFS patients after probiotic intake
Modification of immunological parameters, oxidative stress markers, mood symptoms, and well-being status in CFS patients after probiotic intake: observations from a pilot study, by Letizia Venturini, Sara Bacchi, Enrica Capelli, Lorenzo Lorusso, Giovanni Ricevuti, and Chiara Cusa in Oxidative Medicine … Continue reading
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Tagged Chiara Cusa, Enrica Capelli, Giovanni Ricevuti, immune dysfunction, inflammatory biomarkers, Letizia Venturini, Lorenzo Lorusso, oxidative stress, probiotics, Sara Bacchi
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Immunosignature analysis of ME/CFS – promising diagnostic biomarker
Immunosignature Analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Oliver P Günther, Jennifer L Gardy, Phillip Stafford, Øystein Fluge, Olav Mella, Patrick Tang, Ruth R Miller, Shoshana M Parker, Stephen A Johnston, David M Patrick in Molecular Neurobiology (2018) pp 1-9 [Published online: … Continue reading
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Tagged biomarker, diagnostic marker, Dr David Patrick, Dr Oystein Fluge, immune dysfunction, immunosignature, Jennifer L Gardy, Oliver P Günther, Patrick Tang, Phillip Stafford, Prof Olav Mella, Ruth R Miller, Shoshana M Parker, Stephen A Johnston
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Association of T & NK cell phenotype with the diagnosis of ME/CFS
Research abstract: Association of T and NK cell phenotype with the diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), by Jose Luis Rivas, Teresa Palencia, Guerau Fernández, Milagros Garcia in Front. Immunol., 09 May 2018 Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is … Continue reading
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Tagged diagnosis, Guerau Fernández, immune dysfunction, immunological profile, Jose Luis Rivas, Milagros Garcia, Natural Killer cells, NK cells, T regulatory cells, Teresa Palencia
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Investigation of mast cell toll-like receptor 3 in CFS/ME
Research abstract: Investigation of mast cell toll-like receptor 3 in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Systemic Mastocytosis participants using the novel application of autoMACS magnetic separation and flow cytometry, by C Balinas, T Nguyen, S Johnston, P Smith, D Staines, S Marshall-Gradisnik in Asian … Continue reading
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Tagged C Balinas, Dr Samantha Johnston, Dr Sonya Marshall-Gradisnik, immune dysfunction, mast cells, MCPs, P Smith, Prof Donald Staines, T Nguyen, TLR3, toll-like receptors, white blood cells
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Physiological post-exertional abnormalities in ME & CFS
Review article extracts: Abstract: Post-exertional “malaise” is a hallmark symptom of Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS). Various abnormalities, including abnormal physiological responses to exertion, can account for post-exertional “malaise” and “exercise avoidance”. Since these abnormalities are not … Continue reading
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Tagged energetics, exercise intolerance, Exercise physiology, Exercise Physiology; Energetics; Immune System, immune dysfunction, Oxidative and nitrosative stress, Post-exertional malaise
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Low NK cell activity differs in ME/CFS & MS
Research abstract: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Multiple Sclerosis (MS) patients suffer from debilitating fatigue which is not alleviated by rest. In addition to the fatigue related symptoms suffered by CFS/ME and MS patients, dysfunction of the immune system … Continue reading
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Tagged Dr Sonya Marshall-Gradisnik, immune dysfunction, MS, Multiple Sclerosis, Natural Killer cells, NK cells
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Low NK Cell activity in CFS and is related to severity
Review abstract: Background: Natural killer (NK) cells act as an immune surveillance against invading pathogens and tumors. NK cell cytotoxicity (NKCC) has been reported to be decreased in patients with CFS. Methods: The objective of this review was to conduct … Continue reading
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Tagged immune dysfunction, Natural Killer cells, NK cells, severe ME
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