Tag Archives: cerebral blood flow

Cerebral blood flow & heart rate variability predict fatigue severity in patients with CFS

Research abstract: Cerebral blood flow and heart rate variability predict fatigue severity in patients with chronic fatigue syndrome, by Jeff Boissoneault, Janelle Letzen, Michael Robinson, & Roland Staud in Brain Imaging Behav. 2018 May 31 [Epub ahead of print] Prolonged, … Continue reading

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Cerebral blood flow and heart rate variability in CFS

Cerebral blood flow and heart rate variability in Chronic Fatigue Syndrome: a randomized cross-over study, by Anneleen Malfliet, Roselien Pas, Raf Brouns, Joris De Win, Samar M Hatem, Mira Meeus, Kelly Ickmans, Robbert-Jan van Hooff, and Jo Nijs in heart 2018; 21:E13-E24 BACKGROUND: Pain, fatigue, and concentration difficulties … Continue reading

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Increase in the Regional Cerebral Blood Flow following Waon Therapy in Patients with CFS

Research abstract: Increase in the Regional Cerebral Blood Flow following Waon Therapy in Patients with Chronic Fatigue Syndrome: A Pilot Study, by  T Munemoto, Y Soejima, A Masuda, Y Nakabeppu, C Tei, in Intern Med. 2017;56(14):1817-1824 [Epub 2017 Jul 15] Objective: … Continue reading

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Brain & spinal fluid abnormalities in CFS are not affected by psychiatric comorbidity

Research highlights: As a group, CFS patients have higher brain ventricular lactate, more abnormal spinal fluid results, lower brain GSH, and reduced cerebral blood flow relative to healthy sedentary controls Psychiatric comorbidity does not influence any of these potential biological … Continue reading

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Abnormal cerebral blood flow found in ME/CFS by ASL fMRI

Research abstract: BACKGROUND Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by severe fatigue and neurocognitive dysfunction. Recent work from our laboratory and others utilizing arterial spin labeling functional magnetic resonance imaging (ASL) indicated that ME/CFS patients have … Continue reading

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Abnormal blood flow & connectivity found in ME/CFS brains

Research abstract: Although altered resting-state functional connectivity is a characteristic of many chronic pain conditions it has not yet been evaluated in patients with chronic fatigue. Our objective was to investigate the association between fatigue and altered resting-state functional connectivity … Continue reading

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Cerebral blood flow & impaired neurocognition in POTS

Research abstract We hypothesize that upright cognitive impairment in patients with postural tachycardia syndrome (POTS) is caused by reduced cerebral blood flow (CBF). The CBF velocity (CBFv) measured by transcranial Doppler ultrasound decreased excessively during 70° tilt in a minority … Continue reading

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Poor blood flow leads to cognitive problems in FM

Abstract Objective: There is ample evidence for cognitive deficits in fibromyalgia syndrome (FMS). The present study investigated cerebral blood flow responses during arithmetic processing in FMS patients and its relationship with performance. The influence of clinical factors on performance and … Continue reading

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Reduced blood flow following reduced nitrergic nitric oxide in POTS

Abstract Cognitive deficits are characteristic of postural tachycardia syndrome (POTS). Intact nitrergic nitric oxide (NO) is important to cerebral blood flow (CBF) regulation, to neurovascular coupling, and to cognitive efficacy. POTS patients often experience defective (NO) mediated vasodilation caused by … Continue reading

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Blood flow increases in the brain in POTS

Abstract Decreased upright cerebral blood flow (CBF) with hyperpnea and hypocapnia is seen in a minority of patients with postural tachycardia syndrome (POTS). More often, CBF is not decreased despite upright neurocognitive dysfunction. This may result from time-dependent changes in … Continue reading

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