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MtDNA population variation in ME/CFS in two populations
MtDNA population variation in Myalgic encephalomyelitis/ Chronic fatigue syndrome in two populations: a study of mildly deleterious variants, by Marianne Venter, Cara Tomas, Ilse S Pienaar, Victoria Strassheim, Elardus Erasmus, Wan-Fai Ng, Neil Howell, Julia L Newton, Francois H Van … Continue reading
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Tagged Cara Tomas, Dr Joanna Elson, Elardus Erasmus, Francois H Van der Westhuizen, Ilse S Pienaar, Marianne Venter, mitochondrial DNA, mitochondrial dysfunction, mtDNA, Neil Howell, Prof Julia Newton, South Africa, Victoria Strassheim, Wan-Fai Ng
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Hanson & co defend mtDNA research findings
Article abstract: Earlier this year, we described an analysis of mitochondrial DNA (mtDNA) variants in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) patients and healthy controls. We reported that there was no significant association of haplogroups or singe nucleotide polymorphisms (SNPs) with … Continue reading
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Tagged mitochondrial DNA, mtDNA, Prof Maureen Hanson
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Selfish mitochondria implicated in a variety of diseases
Vanderbilt University press release, 12 July 2016: Selfish mitochondria implicated in a variety of diseases Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual. Mitochondria are special organelles found in … Continue reading
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Tagged mtDNA, Prof Maulik Patel, selfish mitochondria, Vanderbilt University
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A new approach for investigating mitochondrial DNA in ME
Research abstract: In mitochondrial research, many investigators have examined the association between mitochondrial DNA (mtDNA) variants in rare as well as common complex diseases. Previous studies at the CHM (NWU) detected three known pathogenic mtDNA variants (m.7497G>A, m.9185T>C and m.10197G>A) at … Continue reading
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Tagged bioenergetics, haplogroups, mitochondrial dysfunction, mtDNA, Seahorse XF analyser
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