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Down-regulation of renin-aldosterone and antidiuretic hormone systems in ME/CFS
Research abstract: BACKGROUND: Central nervous system dysfunction associated with myalgic encephalomyelitis (ME) has been postulated as the cause of chronic fatigue syndrome (CFS). A small heart or reduced left ventricular volume with reduced cardiac output has been reported to be … Continue reading
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Tagged arginine vasopressin, blood pressure, Desmopressin, hormones, K Miwa, orthostatic intolerance, small heart
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Survey of treatment strategies for ME/CFS
Research abstract: Background: The treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) symptoms poses significant challenges. Purpose: To enumerate current clinical treatment strategies for ME/CFS. Methods: A survey was deployed via the Internet to eleven expert clinicians in ME/CFS. The experts … Continue reading
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Tagged bupropion, Dr Suzanne Vernon, drugs, orthostatic intolerance, Sleep solutions, Spyros N. Deftereos
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TMD in CFS is indicator of greater autonomic dysfunction
Research abstract: Background: Chronic fatigue syndrome (CFS) is heterogeneous in nature, yet no clear subclassifications currently exist. There is evidence of dysautonomia in almost 90% of patients and CFS is often co-morbid with conditions associated with autonomic nervous system (ANS) dysfunction, such as … Continue reading
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Tagged autonomic dysfunction, dysautonomia, Lucy J Robinson, orthostatic intolerance, Prof Julia Newton, subgroups, temporomandibular disorder, TMD
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Severity of POT fluctuates in ME
Research abstract: Central nervous system dysfunction with myalgic encephalomyelitis (ME) has been suggested as the main cause of chronic fatigue syndrome. Fluctuation of the symptom severity and hierarchy is a characteristic feature in ME patients. The characteristics of the sympathetic … Continue reading
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Tagged orthostatic intolerance, postural orthostatic tachycardia syndrome, POTS
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Clonidine has little effect on autonomic cardiovascular & orthostatic symptoms in adolescents with CFS
Research abstract: Background: Chronic Fatigue Syndrome (CFS) is a common and disabling condition in adolescence with few treatment options. A central feature of CFS is orthostatic intolerance and abnormal autonomic cardiovascular control characterized by sympathetic predominance. We hypothesized that symptoms … Continue reading
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Tagged abnormal autonomic cardiovascular control, adolescents, clonidine, NorCAPITAL project, Norway, orthostatic intolerance, teenagers, young people
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Orthostatic intolerance syndromes have different biochemical, autonomic and hemodynamic parameters
Research abstract: INTRODUCTION AND OBJECTIVES: Orthostatic intolerance (OI) syndromes are a confusing topic and determining a specific diagnosis to achieve optimal treatment can be troublesome. We sought to assess biomarker, hemodynamic and autonomic variables in OI patients (autonomic dysfunction [AD], … Continue reading
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Tagged AD, autonomic dysfunction, neurally mediated syncope, NMS, orthostatic intolerance, postural orthostatic tachycardia syndrome, POTS
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HPV vaccine is suspected cause of POTs
Research abstract: BACKGROUND Infections with human papilloma virus (HPV) can result in cervical, oropharyngeal, anal, and penile cancer and vaccination programs have been launched in many countries as a preventive measure. We report the characteristics of a number of patients … Continue reading
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Tagged HPV, human papilloma virus, orthostatic intolerance, postural orthostatic tachycardia syndrome, POTS, vaccine
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ME in children – Specialist lectures on video
Seminar on children and young people with ME/CFS – 2014 On November 12, 2014 the National Association for ME in Sweden organized a seminar on children and young people with ME/CFS. The seminar was conducted in cooperation with RME Stockholm and … Continue reading
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Tagged children, Dr Amolak Bansal, Dr Nigel Speight, Nathalie Gillberg, OI, orthostatic intolerance, paediatric ME, Peter C Rowe, videos
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Increasing blood pressure with phenylephrine reduces OI symptoms
Research abstract Chronic Fatigue Syndrome (CFS), with orthostatic intolerance is characterized by neurocognitive deficits, impaired working memory, concentration, and information processing. In CFS, upright tilting (HUT) caused decreased cerebral blood flow velocity (CBFv) related to yperpnea/hypocapnia and impaired cerebral autoregulation; … Continue reading
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Tagged blood pressure, CBF, HUT, orthostatic intolerance, phenylephrine, tilt table test, upright tilting
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Orthostatic Intolerance in adolescents
Research abstract (provisional) Background Orthostatic intolerance is common in chronic fatigue syndrome (CFS), and several studies have documented an abnormal sympathetic predominance in the autonomic cardiovascular response to gravitational stimuli. The aim of this study was to explore whether the … Continue reading
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Tagged adolescents, orthostatic intolerance, tilt table
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