Tag Archives: Sjogren’s syndrome

Reduction of glucocorticoid receptor function in CFS – no causal link to childhood trauma

Research abstract: Reduction of glucocorticoid receptor function in CFS, by Megan Lynn, Laura Maclachlan, Andreas Finkelmeyer, James Clark, James Locke, Stephen Todryk, Wan-Fai Ng, Julia L Newton, Stuart Watson in Mediators of Inflammation [Preprint April 20, 2018] Glucocorticoid receptor (GR) function may … Continue reading

Posted in News | Tagged , , , , , , , , , , , , | Comments Off on Reduction of glucocorticoid receptor function in CFS – no causal link to childhood trauma

Fatigue relating mechanism in Sjögren’s syndrome

Research abstract: OBJECTIVE: Chronic fatigue is a common, disabling and poorly understood phenomenon. Recent studies indicate that epigenetic mechanisms may be involved in the expression of fatigue, a prominent feature of primary SS (pSS). The aim of this study was … Continue reading

Posted in News | Tagged , , | Comments Off on Fatigue relating mechanism in Sjögren’s syndrome

Cellular defence mechanisms cause fatigue in Sjorgen’s syndrome

Research abstract: Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system is activated, heat shock proteins (HSPs) are … Continue reading

Posted in News | Tagged , | Comments Off on Cellular defence mechanisms cause fatigue in Sjorgen’s syndrome

55 genes predict fatigue level in Sjögren’s Syndrome

Research abstract: BACKGROUND: Fatigue is a debilitating condition with a significant impact on patients’ quality of life. Fatigue is frequently reported by patients suffering from primary Sjögren’s Syndrome (pSS), a chronic autoimmune condition characterised by dryness of the eyes and … Continue reading

Posted in News | Tagged , , , | Comments Off on 55 genes predict fatigue level in Sjögren’s Syndrome

Medications cause 70% of dry eyes, mouth etc. in CFS

Chronic fatigue syndrome (CFS) is a heterogeneous and multisystemic disorder of unknown pathogenesis and etiology. It is characterized by prolonged generalized and abnormal fatigue post-exercise (98%), recurrent headache (90%) and problems of concentration and memory (85%) that have lasted for … Continue reading

Posted in News | Tagged , , , , , , , , , , , , , | Comments Off on Medications cause 70% of dry eyes, mouth etc. in CFS