Category Archives: News
Neuroimaging of Central Sensitivity Syndromes
Research abstract: Central sensitivity syndromes are characterized by distressing symptoms, such as pain and fatigue, in the absence of clinically obvious pathology. The scientific underpinnings of these disorders are not currently known. Modern neuroimaging techniques promise new insights into mechanisms … Continue reading
Abnormal cerebral blood flow found in ME/CFS by ASL fMRI
Research abstract: BACKGROUND Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by severe fatigue and neurocognitive dysfunction. Recent work from our laboratory and others utilizing arterial spin labeling functional magnetic resonance imaging (ASL) indicated that ME/CFS patients have … Continue reading
The effect of significant other responses on CFS symptom fluctuations
Research abstract: Objective: Significant other responses to patients’ symptoms are important for patient illness outcomes in chronic fatigue syndrome (CFS/ME); negative responses have been associated with increased patient depression, whilst increased disability and fatigue have been associated with solicitous significant other responses. The current … Continue reading
The effect of subjective sleep on fatigue in CFS
Research abstract: Study Objectives: This study aimed to (1) examine the relationship between subjective and actigraphy-defined sleep, and next-day fatigue in chronic fatigue syndrome (CFS); and (2) investigate the potential mediating role of negative mood on this relationship. We also … Continue reading
Dr David Maughan discusses ME, it’s treatment and it’s difficult politics
Researcher Dr. David Maughan of the University of Vermont, and Advocate Rik Carlson discuss the disease, it’s treatment, and the difficult politics surrounding this disease in particular, in the Paradigms blog: What is Myalgic Encephalomyelitis, also known as Chronic Fatigue … Continue reading
Rethinking childhood adversity in CFS
Research abstract: Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data … Continue reading
Anti-citrullinated protein antibodies in CFS
The Vermont CFIDS Association reports on a recent pilot study and invites contributions to enable further research: While preliminary, the results from this University of Vermont study is the first evidence for the potential existence of autoantibodies in ME/CFS, indicative … Continue reading
Junior doctors’ experiences of managing patients with MUS
Research abstract: Objectives: To explore junior doctors’ knowledge about and experiences of managing patients with medically unexplained symptoms (MUS) and to seek their recommendations for improved future training on this important topic about which they currently receive little education. Design: … Continue reading
CFS/ME pathophysiology, diagnosis & treatment overview
Review abstract: The underlying pathophysiology in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is unclear, and there is disagreement in the field over diagnostic criteria and treatments. Here, we review the literature and comment on the debate around this condition. Chronic fatigue … Continue reading
Interview with Dr Judy Mikovits: a medical whistleblower’s tale
Global Freedom Movement video interview: Drugs, Disease and Deception: A Medical Whistleblower’s Tale with Judy Mikovits Phd Meet Dr. Judy Mikovits, a passionate research molecular biologist and biochemist; wrongfully jailed with her career destroyed forever because she dared to publish … Continue reading



