Tag Archives: post-exertional deterioration

Advances in understanding the pathophysiology of CFS

Advances in understanding the pathophysiology of Chronic Fatigue Syndrome, by Anthony L Komaroff in JAMA [Preprint July 5, 2019]   Viewpoint extracts: When does an illness become a disease? When the underlying biological abnormalities that cause the symptoms and signs of the … Continue reading

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Prof Jason invites you to take part in research into abnormal response to exertion

DePaul University, Chicago questionnaire, by Prof Leonard Jason: Abnormal Response to Physical and/or Cognitive Exertion in ME and CFS We are conducting a research study because we are trying to learn more about the experience of abnormal responses to physical and/or … Continue reading

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The search for a non invasive diagnostic test for ME/CFS

Solve ME/CFS Initiative blog post, 13 January 2013: Non-Invasive Diagnostic Test Project Seeks to Detect ME/CFS This week, we highlight the Cathleen J. Gleeson PhD Fund and our collaborative partnership with the University of Washington on diagnostic testing in ME/CFS. This … Continue reading

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Neuromuscular strains in ME/CFS

ME Research UK research article, 2 August 2016: Neuromuscular strains In the diagnosis and assessment of ME/CFS, there is a great need for simple objective measures that can differentiate the condition from other chronic illnesses, particularly after 24 or 48 … Continue reading

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Exercise triggers gut changes comment by Cort Johnson

Cort Johnson comments on recent research: Exercise triggers gut changes in Chronic Fatigue Syndrome (ME/CFS) December 21 2015 It seems every week brings more news highlighting the surprising importance the gut has on our health. A couple of years ago … Continue reading

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Changes in gut & plasma microbiome following exercise challenge in ME/CFS

Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease characterized by intense and debilitating fatigue not due to physical activity that has persisted for at least 6 months, post-exertional malaise, unrefreshing sleep, and accompanied by a number of secondary … Continue reading

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Oxidative phosphorylation & lactic acid excretion are impaired in severe ME

Case study abstract: Background: In this study the muscle bioenergetic function in response to exercise in severe ME was explored to see if the underlying metabolic problem in ME, responsible for the severe difficulties with trivial exercise, and the severe loss … Continue reading

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Child abuse allegations in ME unfounded

Abstract There is no cure for ME (Myalgic Encephalomyelitis). In its absence, management regimes are prescribed, typically based on cognitive behavioural therapy (CBT) and graded exercise therapy (GET). In the case of children this may involve the application of Child … Continue reading

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