Category Archives: News
Co-enzyme Q10 does not help fatigue in post-polio patients
Research abstract: OBJECTIVE: To determine if coenzyme Q10 alleviates fatigue in the late-onset sequelae of poliomyelitis. DESIGN: Parallel-group, randomized, placebo-controlled trial. BACKGROUND SETTING: Coenzyme Q10 has been shown to boost muscle energy metabolism in post-polio subjects but it does not … Continue reading
Prof Coyne’s PACE trial FOI request refused as considered ‘vexatious’
Prof James Coyne has received a reply from the authors of the PACE trial refusing access to data: 11 December 2015 Dear Professor Coyne, Request for information under the Freedom of Information Act 2000 (“the Act”) Further to your recent … Continue reading
B-cell function in patients with ME/CFS
Research summary: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a heterogeneous condition of unknown etiology characterized by multiple symptoms including fatigue, post-exertional malaise and cognitive impairment, lasting for at least 6 months. Recently, two clinical trials of B-cell depletion therapy with rituximab (anti-CD20) reported convincing … Continue reading
DOPE: Delayed Onset Post Exertional fatigue
Dr John L Whiting explains why he thinks the term DOPE is better than PEM or PENE: One of the biggest nuisances that ME/CFS sufferers have to contend with is the post exertional fatigue component. This issue was an aspect … Continue reading
IBS subtypes
Research abstract: Background: Irritable bowel syndrome (IBS) is classified into subtypes according to bowel habit. Objective: To investigate whether there are differences in clinical features, comorbidities, anxiety, depression and body mass index (BMI) among IBS subtypes. Methods: The study group included … Continue reading
Interview with Dr Michael Van Elzakker about CFS & vagus nerve infection
Harvard neuroscientist Dr Michael Van Elzakker: Chronic fatigue vagus nerve link: The low histamine chef interview with Yasmina Ykelenstam, 8 Dec 2015: In today’s interview Harvard and Tufts neuroscientist Dr Michael Van ElZakker shares his fascinating new paper Chronic Fatigue from Vagus … Continue reading
Researchers investigate the ‘pathways of pain’
Researchers investigate the ‘pathways of pain’ in NHS Choices, Monday December 7 2015 While rare, there are some people who are unable to feel pain “Breakthrough could lead to ‘super painkillers’,” the Mail Online reports. Researchers have investigated a sodium … Continue reading
$500,000 grant for the OMF ME/CFS Severely Ill-BIG DATA Study
A very generous anonymous donor has expressed confidence in Open Medicine Foundation (OMF) research by donating $500,000 to expand the OMF ME/CFS Severely Ill Big Data Study. Just a few months ago, they reached their goal of $1 million to do … Continue reading
Skin conditions in POTS are common and diverse
Research abstract: Background and Purpose: Postural tachycardia syndrome (POTS) is a syndrome of orthostatic intolerance in the setting of excessive tachycardia with orthostatic challenge, and these symptoms are relieved when recumbent. Apart from symptoms of orthostatic intolerance, there are many … Continue reading
Abnormal brain activity found in women with CFS
Research abstract: The biological underpinnings of the psychological factors characterizing chronic fatigue syndrome (CFS) have not been extensively studied. Our aim was to evaluate alterations of resting-state functional connectivity in CFS patients. Participants comprised 18 women with CFS and 18 … Continue reading
