Category Archives: News

Reduced blood flow following reduced nitrergic nitric oxide in POTS

Abstract Cognitive deficits are characteristic of postural tachycardia syndrome (POTS). Intact nitrergic nitric oxide (NO) is important to cerebral blood flow (CBF) regulation, to neurovascular coupling, and to cognitive efficacy. POTS patients often experience defective (NO) mediated vasodilation caused by … Continue reading

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Cerebrospinal fluid pressure may be problem in CFS

Abstract   Objective Unsuspected idiopathic intracranial hypertension (IIH) is found in a significant minority of patients attending clinics with named headache syndromes, if it is specifically sought out. Chronic fatigue syndrome is frequently associated with headache. Could the same be … Continue reading

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ME/CFS brain and tissue bank protocol

Abstract (provisional)   Background Our aim, having previously investigated through a qualitative study involving extensive discussions with experts and patients the issues involved in establishing and maintaining a disease specific brain and tissue bank for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), … Continue reading

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Why those with treatable diseases get more sympathy than ME

Martha Gill, a blogger on politics and neurosciences comments: According to reports, a third of people who think they have ME may actually be suffering from something else – a disease called postural tachycardia syndrome (PoTS). It has the same symptoms … Continue reading

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POTS affects mostly young women

Abstract Objective To examine a large UK cohort of patients with postural tachycardia syndrome (PoTS), to compare demographic characteristics, symptoms and treatment of PoTS at one centre compared to the largest patient group PoTS UK and to verify if their … Continue reading

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Post-traumatic hypopituitarism (PTHP) often misdiagnosed as CFS

Patients misdiagnosed with CFS when they have brain damage Post-traumatic hypopituitarism (PTHP) is often cause by head injury Symptoms include depression, obesity, fatigue and chronic pain Numerous studies have shown that between 20 and 30 per cent of the 135,000 … Continue reading

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Blood flow increases in the brain in POTS

Abstract Decreased upright cerebral blood flow (CBF) with hyperpnea and hypocapnia is seen in a minority of patients with postural tachycardia syndrome (POTS). More often, CBF is not decreased despite upright neurocognitive dysfunction. This may result from time-dependent changes in … Continue reading

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Neuropsychological impairment in women with CFS

Abstract This study examines neuropsychological impairments associated with chronic fatigue syndrome (CFS) and explores their association with related clinical factors. Sixty-eight women with CFS were assessed with a neuropsychological battery. Raw scores were adjusted for age and gender and were … Continue reading

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Brain neuron damage level in CFS similar to MS

Abstract   Objective: This study examined the levels of a major regulator of neuronal survival, brain derived neurotrophic factor (BDNF) in two populations; individuals with multiple sclerosis and chronic fatigue syndrome. BDNF is a protein involved in the maintenance and … Continue reading

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Relationship found between CFS and infections

Introduction: Chronic Fatigue Syndrome (CFS) is a complex disorder with a common set of core symptoms and with many secondary symptoms. Underlying chronic infection has been advocated as a contributing factor to CFS, yet its role and the extent of … Continue reading

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