Tag Archives: Natural Killer cells

Treatment research: …restoration using Naltrexone in natural killer cells of ME/CFS patients

Posted on 02/23/2022 by wames

Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients, by Natalie Eaton-Fitch, Stanley Du Preez, Hélène Cabanas, Katsuhiko Muraki, Donald Staines & Sonya Marshall-Gradisnik in Journal of Translational Medicine volume 20, … Continue reading →

Posted in News | Tagged , , , , , , , , , | Comments Off on Treatment research: …restoration using Naltrexone in natural killer cells of ME/CFS patients

Research: Potential therapeutic benefit of Low Dose Naltrexone in ME/CFS

Posted on 07/16/2021 by wames

Potential Therapeutic Benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: role of Transient Receptor Potential Melastatin 3 Ion channels in pathophysiology and treatment, by Helene Cabanas,  Katsuhiko Muraki,  Natalie Eaton-Fitch,  Donald Ross Staines and Sonya Marshall-Gradisnik in … Continue reading →

Posted in News | Tagged , , , , , , , , , , | Comments Off on Research: Potential therapeutic benefit of Low Dose Naltrexone in ME/CFS

An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

Posted on 12/28/2019 by wames

An investigation into the modulation of T cell phenotypes by amitriptyline and nortriptyline, by JonathanRoyds, Melissa J Conroy, Margaret R Dunne, Connail McCrory, Joanne Lysaght in European Neuropsychopharmacology, Dec 2019[doi.org/10.1016/j.euroneuro.2019.12.106]   Research abstract: Amitriptyline is prescribed for treating the symptoms … Continue reading →

Posted in News | Tagged , , , , , , , , , , , , | Comments Off on An investigation into the modulation of T cell phenotypes by amitriptyline & nortriptyline

Transient receptor potential melastatin 2 channels are overexpressed in ME/CFS patients

Posted on 12/18/2019 by wames

Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients, by Cassandra Balinas, Helene Cabanas, Donald Staines, Sonya Marshall-Gradisnik in Journal of Translational Medicine Vol 17, #1, p 401, December 3, 2019   Research abstract: Background: Myalgic … Continue reading →

Posted in News | Tagged , , , , , , , , , | Comments Off on Transient receptor potential melastatin 2 channels are overexpressed in ME/CFS patients

A systematic review of natural killer cells profile & cytotoxic function in ME/CFS

Posted on 11/21/2019 by wames

A systematic review of natural killer cells profile and cytotoxic function in myalgic encephalomyelitis/chronic fatigue syndrome, by Natalie Eaton-Fitch, Stanley du Preez, Hélène Cabanas, Donald Staines & Sonya Marshall-Gradisnik in Systematic Reviews vol 8, no: 279 (2019)   Review abstract: … Continue reading →

Posted in News | Tagged , , , , , | Comments Off on A systematic review of natural killer cells profile & cytotoxic function in ME/CFS

Naltrexone restores impaired Transient Receptor Potential Melastatin 3 ion channel function in Natural Killer Cells from ME/CFS

Posted on 10/31/2019 by wames

Naltrexone restores impaired Transient Receptor Potential Melastatin 3 ion channel function in Natural Killer Cells from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients, by Helene Cabanas,  Katsuhiko Muraki,  Donald Staines and Sonya Marshall-Gradisnik in Front. Immunol., 31 October 2019 [https://doi.org/10.3389/fimmu.2019.02545]   Research … Continue reading →

Posted in News | Tagged , , , , , , , , | Comments Off on Naltrexone restores impaired Transient Receptor Potential Melastatin 3 ion channel function in Natural Killer Cells from ME/CFS

Validation of impaired TRPM3 ion channel activity in natural killer cells from CFS/ME

Posted on 05/21/2019 by wames

Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in natural killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients, by H Cabanas, K Muraki, C Balinas, N Eaton-Fitch, D Staines, S Marshall-Gradisnik in Mol Med. 2019 Apr … Continue reading →

Posted in News | Tagged , , , , , , , , , | Comments Off on Validation of impaired TRPM3 ion channel activity in natural killer cells from CFS/ME

Cellular immune function in ME/CFS: increased MAIT cell frequency

Posted on 04/17/2019 by wames

Cellular immune function in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), by Jacqueline M Cliff, Elizabeth C King, Ji-Sook Lee, Nuno Sepulveda, Asia-Sofia Wolf, Caroline Kingdon, Erinna Bowman, Hazel M. Dockrell, Luis C. Nacul, Eliana Lacerda, Eleanor Riley in Front. Immunol., 16 April … Continue reading →

Posted in News | Tagged , , , , , , , , , , , , , , , | Comments Off on Cellular immune function in ME/CFS: increased MAIT cell frequency

Decreased expression of the CD57 molecule in T Lymphocytes of patients with CFS

Posted on 04/05/2019 by wames

Decreased Expression of the CD57 Molecule in T Lymphocytes of Patients with Chronic Fatigue Syndrome, by P Espinosa, J M Urra in  Mol Neurobiol (2019) [Online: 21 March 2019] Research abstract: The chronic fatigue syndrome (CFS) is characterized by a prolonged … Continue reading →

Posted in News | Tagged , , , , , , , | Comments Off on Decreased expression of the CD57 molecule in T Lymphocytes of patients with CFS

Loss of transient receptor potential Melastatin 3 ion channel function in natural killer cells from CFS/ME

Posted on 08/29/2018 by wames

Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from CFS/ME patients by Hélène Cabanas, Katsuhiko Muraki, Natalie Eaton, Cassandra Balinas, Donald Staines and Sonya Marshall-Gradisnik in Molecular Medicine 2018 24:44 [Published: 14 August 2018] Research abstract: … Continue reading →

Posted in News | Tagged , , , , , , , , , , , | Comments Off on Loss of transient receptor potential Melastatin 3 ion channel function in natural killer cells from CFS/ME