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Searching for serum antibodies to neuronal proteins in patients with ME/CFS
Searching for serum antibodies to neuronal proteins in patients with Myalgic Encephalopathy/Chronic Fatigue Syndrome, by Maria Pia Giannoccaro, Judith Cossins, Kari Sorland, Oystein Fluge, Angela Vincent in Clinical Therapeutics Vol 41, Issue 5, May 2019, Pages 836-847 Research abstract: Purpose: … Continue reading
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Tagged Angela Vincent, antibodies, Dr Oystein Fluge, Judith Cossins, Kari Sorland, LRP4, Maria Pia Giannoccaro, neuronal surface antigens, NMDA receptor
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Antibodies against GPCR – their role in CFS/ME
Review abstract: Antibodies Against GPCR, by Carlotta Meyer, Harald Heidecke in Front Biosci (Landmark Ed). 2018 Jun 1;23:2177-2194. G-protein-coupled receptors (GPCRs) are the largest family of receptors in humans. GPCRs are seven-transmembrane receptors that are activated by the binding of a ligand … Continue reading
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Tagged antibodies, Carlotta Meyer, G-protein-coupled receptors, GPCR, Harald Heidecke, ligand
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Norwegian Rituximab studies update
Helse Bergen blog post, 29 Sep 29017: RituxME B-lymphocyte depletion using the anti-CD20 antibody rituximab (Mabthera®) in Myalgic Encephalopathy/Chronic Fatigue Syndrome (“RituxME”) RituxME is a multicentre study conducted in five study centres in Norway: the Oncology Department at Haukeland University … Continue reading
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Tagged antibodies, Dr Oystein Fluge, Norway, Prof Olav Mella, rituximab, RituxME
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Rituximab leads to B-cell depletion and remission in ME/CFS
Research abstract: Background: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab … Continue reading
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Tagged antibodies, B-cell, Dr Olav Mella, Dr Oystein Fluge, New Scientist, rituximab
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