Tag Archives: Dr Oystein Fluge

B-Lymphocyte depletion in patients with ME/CFS: the final rituximab trial results

B-lymphocyte depletion in patients With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: a randomized, double-blind, placebo-controlled trial by Oystein Fluge, Ingrid G. Rekeland, Katarina Lien, Hanne Thurmer, Petter C. Borchgrevink, Christoph Schafer, Kari Sorland, Jorg Assmus, Irini Ktoridou-Valen, Ingrid Herder, Merethe E. … Continue reading

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Immunosignature analysis of ME/CFS – promising diagnostic biomarker

Immunosignature Analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Oliver P Günther, Jennifer L Gardy, Phillip Stafford, Øystein Fluge, Olav Mella, Patrick Tang, Ruth R Miller, Shoshana M Parker, Stephen A Johnston, David M Patrick in Molecular Neurobiology (2018) pp 1-9 [Published online: … Continue reading

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Norwegian rituximab trial reports negative results

The Norwegian Rituximab trial reports negative results ahead of the publication of the full results. Attempts are now under way to determine the best way forward in understanding what has been learned and how to find out which patients may still benefit from … Continue reading

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Norwegian Rituximab studies update

Helse Bergen blog post, 29 Sep 29017: RituxME B-lymphocyte depletion using the anti-CD20 antibody rituximab (Mabthera®) in Myalgic Encephalopathy/Chronic Fatigue Syndrome (“RituxME”) ​RituxME is a multicentre study conducted in five study centres in Norway: the Oncology Department at Haukeland University … Continue reading

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Metabolic switch may bring on CFS

New Scientist article, by Andy Coghlan, 13 February 2016: Metabolic switch may bring on chronic fatigue syndrome It’s as if a switch has been flicked. Evidence is mounting that chronic fatigue syndrome (CFS) is caused by the body swapping to … Continue reading

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Video lectures from English & Norwegian researchers in Norwich

Invest in ME public talks in Norwich on ME/CFS biomedical research, published 7 Feb 2017 An event held in Norwich in January 2017 gave the public a chance to hear about some of the biomedical research being undertaken on the … Continue reading

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UK Rituximab trial collaboration between Norway & UK featured on BBC

BBC Look East video clip, 26 January 2017: Research in Norwich could offer ME/CFS breakthrough  Researchers in Norwich are teaming up with researchers from Norway to collaborate on ME/CFS research. The researchers say they believe that ME is reversible, and … Continue reading

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Discussion of Fluge’s finding of key metabolic enzyme impairment in ME/CFS

TV2 interview with Dr Øystein Fluge on his latest research on ME/CFS – in Norwegian with English subtitles. Begins with a man who is very severely affected by ME. (11 minutes 23 seconds)    Watch video   Medscape Medical news article, 13 January 2017: … Continue reading

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Fuel shortage: Norwegian study expands on energy problem in ME/CFS

Health rising blog post, by Cort Johnson, 27 Dec 2016: Fuel shortage: Norwegian study Expands on Energy Problem in Chronic Fatigue Syndrome (ME/CFS) Fluge and Mella seem to be working at almost lightning speed. Besides managing their huge Rituximab study … Continue reading

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Metabolic profiling indicates impaired pyruvate dehydrogenase function in ME/CFS

Research abstract: Myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) is a debilitating disease of unknown etiology, with hallmark symptoms including postexertional malaise and poor recovery. Metabolic dysfunction is a plausible contributing factor. We hypothesized that changes in serum amino acids may disclose … Continue reading

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