Tag Archives: biomarkers
MicroRNAs as potential biomarkers in ME/CFS
ME Research UK comments on recent research: MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME), by RD Petty, NE McCarthy, R Le Dieu, J R … Continue reading
Illness progression in CFS: immune signature changes
Research abstract: Background: Validation of biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) across data sets has proven disappointing. As immune signature may be affected by many factors, our objective was to explore the shift in discriminatory cytokines across ME/CFS subjects … Continue reading
Spanish patient-led immune biomarker study seeking funding
ASSSEMBiomedics, a new ME patient led research and treatment group in Barcelona, Spain, is starting a new ME Immune Biomarker research study with samples from 100 people with ME and from 100 healthy controls. For this new project ASSSEMBiomedics needs … Continue reading
Dr Alan Light lecture on Youtube Thurs 3 Dec 2am
Free Education Meeting: “Partnerships to Accelerate Biomarker & Mechanism Discovery in ME/CFS and Fibromyalgia” Presented by Dr. Alan Light Wednesday, December 2nd, 2015 8pm Central / Thursday 2am GMT Salt Lake County Complex, North Building, 2001 S. State Street, SLC, … Continue reading
Neuro-inflammatory and oxidative fatigue (NIOF) – new case definition of ME
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) or Myalgic Encephalomyelitis (ME) is characterized by neuro-psychiatric (e.g. depression, irritability, sleep disorders, autonomic symptoms and neurocognitive defects) and physio-somatic (fatigue, a flu-like malaise, hyperalgesia, irritable bowel, muscle pain and tension) symptoms. New … Continue reading
MicroRNA hope for CFS/ME biomarker
Research abstract Background: MicroRNAs (miRNAs) are known to regulate many biological processes and their dysregulation has been associated with a variety of diseases including Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). The recent discovery of stable and reproducible miRNA in plasma has … Continue reading
SNPs in CFS/ME genes could lead to diagnostic test for CFS/ME subtypes
Research abstract Aims We have reported gene expression changes in patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and the fact that such gene expression data can be used to identify subtypes of CFS/ME with distinct clinical phenotypes. Due to the … Continue reading
Biomarker for fatigue could help validate CFS
Measuring Fatigue Finally? Cort Johnson asks: Has a test that objectively measures fatigue been found? Extract: How to objectively measure fatigue has dogged the Chronic Fatigue Syndrome field for decades. Until researchers can tell how fatigued a person really is … Continue reading
Potential of CFS biomarkers
Abstract Chronic fatigue syndrome (CFS) remains an incompletely characterized illness, in part due to controversy regarding its definition, biological basis and diagnosis. Biomarkers are objective measures that may lead to improvements in our understanding of CFS by providing a more … Continue reading
Low-grade inflammation has a role in the development of fatigue
Abstract BACKGROUND: Although basic research on neuroimmune interactions suggests that inflammatory processes may play a role in the development of fatigue, population-based evidence on this association is limited. This study examined whether plasma C-reactive protein (CRP) and interleukin-6 (IL-6), biomarkers … Continue reading
