Tag Archives: gene expression

Epigenetic components of ME/CFS uncover potential Transposable Element activation

Posted on May 3, 2019 by wames

Epigenetic components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover potential Transposable Element Activation, by  Eloy Almenar-Pérez, Tamara Ovejero PhD, Teresa Sánchez-Fito MSc, José A Espejo BSc, Lubov Nathanson PhD, Elisa Oltra PhD, in Clinical Therapeutics [Published online 23 March 2019] https://doi.org/10.1016/j.clinthera.2019.02.012 … Continue reading →

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CD24 expression & B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS

Posted on November 21, 2018 by wames

CD24 expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome , by Fane K. Mensah, Christopher W Armstrong, Venkat Reddy, Amolak S Bansal, Saul Berkovitz, Maria Leandro … Continue reading →

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The expression signature of very long non-coding RNA in ME/CFS

Posted on August 23, 2018 by wames

The expression signature of very long non-coding RNA in myalgic encephalomyelitis/ chronic fatigue syndrome, by Chin-An Yang, Sandra Bauer, Yu-Chen Ho, Franziska Sotzny, Jan-Gowth Chang, Carmen Scheibenbogen in Journal of Translational Medicine 2018 16:231 [Published: 17 August 2018] Research abstract: Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is … Continue reading →

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Altered B cells found in whole blood gene expression in adolescent CFS

Posted on May 16, 2017 by wames

Research abstract Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival, by Chinh Bkrong Nguyen, Lene Alsøe, Jessica M. Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde … Continue reading →

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Genes, mitochondria, autoimmunity & CFS: Prof Alan Light’s research

Posted on March 27, 2017 by wames

Health rising blog post, by Cort Johnson, 23 Feb 2017: Genes, Mitochondria, Autoimmunity and Chronic Fatigue Syndrome: The Alan Light Talk Dr. Light has said that he wants to do for fatigue what researchers have done for pain; that is … Continue reading →

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A systematic review of the association between fatigue & genetic polymorphisms

Posted on January 18, 2017 by wames

Review abstract: Fatigue is one of the most common and distressing symptoms, leading to markedly decreased quality of life among a large subset of patients with a variety of disorders. Susceptibility to fatigue may be influenced by genetic factors including … Continue reading →

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Mitochondrial proteins as possible biomarkers for subgroups of CFS

Posted on September 30, 2016 by wames

Research abstract: Chronic fatigue syndrome (CFS) is a debilitating and complex disorder characterized by unexplained fatigue not improved by rest. An area of investigation is the likely connection of CFS with defective mitochondrial function. In a previous work, we investigated the proteomic salivary profile … Continue reading →

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Protein kinase gene dysfunction in severe CFS/ME

Posted on August 30, 2016 by wames

Research abstract: Background: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading →

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Gene expression factor analysis used to differentiate CFS, FM and depression

Posted on June 6, 2016 by wames

Research abstract: OBJECTIVE: To determine if independent candidate genes can be grouped into meaningful biologic factors, and whether these factors are associated with the diagnosis of chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS), while controlling for comorbid depression, sex, … Continue reading →

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MicroRNAs as potential biomarkers in ME/CFS

Posted on April 6, 2016 by wames

ME Research UK comments on recent research: MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential Diagnostic Biomarkers in Natural Killer (NK) Cells of Patients with Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME), by RD Petty, NE McCarthy, R Le Dieu, J R … Continue reading →

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