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- Reduced heart rate variability predicts fatigue severity in individuals with CFS/ME
- Recovering from CFS as an intra-active process
- A neuro-inflammatory model can explain the onset, symptoms and flare-ups of ME/CFS
- Paediatric patients with ME/CFS value understanding & help to move on with their lives
- The role of low-grade inflammation in ME/CFS – associations with symptoms
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Tag Archives: gene expression
MicroRNAs as biomarkers of pain intensity in patients with CFS
MicroRNAs as biomarkers of pain intensity in patients with chronic fatigue syndrome, by Hadeel A Al‐Rawaf, Ahmad H Alghadir, Sami A Gabr in Pain Pract. 2019 Jul 8. doi: 10.1111/papr.12817. [Epub ahead of print] Research abstract: BACKGROUND: Numerous experimental models … Continue reading
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Tagged adolescents, Ahmad H Alghadir, children, chronic pain, Dr Sami A Gabr, gene expression, Hadeel A Al‐Rawaf, immune inflammatory genes, microRNAs, miRNAs, teenagers
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Epigenetic components of ME/CFS uncover potential Transposable Element activation
Epigenetic components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover potential Transposable Element Activation, by Eloy Almenar-Pérez, Tamara Ovejero PhD, Teresa Sánchez-Fito MSc, José A Espejo BSc, Lubov Nathanson PhD, Elisa Oltra PhD, in Clinical Therapeutics [Published online 23 March 2019] https://doi.org/10.1016/j.clinthera.2019.02.012 … Continue reading
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Tagged Dr Tamara Ovejero, Eloy Almenar-Pérez, epigenetics, epigenome, gene expression, José A Espejo, long-noncoding RNA, Lubov Nathanson, microRNAs, Prof Elisa Oltra, retrotransposon, Teresa Sánchez-Fito, transposable elements
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The expression signature of very long non-coding RNA in ME/CFS
The expression signature of very long non-coding RNA in myalgic encephalomyelitis/ chronic fatigue syndrome, by Chin-An Yang, Sandra Bauer, Yu-Chen Ho, Franziska Sotzny, Jan-Gowth Chang, Carmen Scheibenbogen in Journal of Translational Medicine 2018 16:231 [Published: 17 August 2018] Research abstract: Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is … Continue reading
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Tagged Carmen Scheibenbogen, Chin-An Yang, expression signature, Franziska Sotzny, gene expression, Jan-Gowth Chang, lncRNAs, long non-coding RNA, Sandra Bauer, Yu-Chen Ho
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Altered B cells found in whole blood gene expression in adolescent CFS
Research abstract Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival, by Chinh Bkrong Nguyen, Lene Alsøe, Jessica M. Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde … Continue reading
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Tagged adolescents, B cells, gene expression, NorCAPITAL project, teenagers
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Genes, mitochondria, autoimmunity & CFS: Prof Alan Light’s research
Health rising blog post, by Cort Johnson, 23 Feb 2017: Genes, Mitochondria, Autoimmunity and Chronic Fatigue Syndrome: The Alan Light Talk Dr. Light has said that he wants to do for fatigue what researchers have done for pain; that is … Continue reading
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Tagged Cort Johnson, exercise intolerance, gene expression, Health rising, mitochondria, molecular receptors, PEM, Prof Alan Light
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Mitochondrial proteins as possible biomarkers for subgroups of CFS
Research abstract: Chronic fatigue syndrome (CFS) is a debilitating and complex disorder characterized by unexplained fatigue not improved by rest. An area of investigation is the likely connection of CFS with defective mitochondrial function. In a previous work, we investigated the proteomic salivary profile … Continue reading
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Tagged biomarkers, gene expression, mitochondrial proteins
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Protein kinase gene dysfunction in severe CFS/ME
Research abstract: Background: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading
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Tagged Anu Chacko, Dr Samantha Johnston, gene expression, Prof Donald Staines, protein kinase genes, Sonya Marshall-Gradisnik
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Gene expression factor analysis used to differentiate CFS, FM and depression
Research abstract: OBJECTIVE: To determine if independent candidate genes can be grouped into meaningful biologic factors, and whether these factors are associated with the diagnosis of chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS), while controlling for comorbid depression, sex, … Continue reading
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Tagged depression, E Iacob, EFA, Fibromyalgia, FM, gene expression, https://en.wikipedia.org/wiki/Exploratory factor analysis, Kathleen C Light, Prof Alan Light
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