Tag Archives: Dr Nancy Klimas

Genetic predisposition for immune system, hormone, & metabolic dysfunction in ME/CFS

Genetic predisposition for immune system, hormone, and metabolic dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a pilot study, by Melanie Perez,  Rajeev Jaundoo,  Kelly Hilton,  Ana Del Alamo,  Kristina Gemayel,  Nancy G. Klimas,  Travis J A Craddock and  Lubov Nathanson in … Continue reading

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Treatment avenues in ME/CFS: a split-gender pharmacogenomic study of gene-expression

Treatment avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a split-gender pharmacogenomic study of gene-expression modules, by Mary G Jeffrey, Lubov Nathanson, Kristina Aenlle, Zachary M Barnes, Mirza Baig, Gordon Broderick, Nancy G Klimas, Mary Ann Fletcher, Travis JA Craddock in Clinical … Continue reading

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Endocrine immune regulation in… women with CFS

Leveraging prior knowledge of endocrine immune regulation in the therapeutically relevant phenotyping of women with Chronic Fatigue Syndrome, by Matthew C Morris, Katherine Cooney, Hooman Sedghamiz, Maria Abreu, Fanny Collado, Elizabeth G Balbin, Travis JA Craddock, Nancy G Klimas, Gordon … Continue reading

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Pharmaceutical interventions in CFS: a literature-based commentary

Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary, by  Spencer Richman, Matthew C Morris, Gordon Broderick, Travis JA Craddock, Nancy G Klimas, Mary Ann Fletcher in Clinical Therapeutics [Available online 11 March 2019] Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome … Continue reading

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System reset? Study suggests Pro-Inflammatory / Autoimmune reset in ME/CFS

Simmaron Research blog post, by Cort Johnson, 4 August 2018: System Reset? Study Suggests Pro-Inflammatory / Autoimmune Reset Occurred in Chronic Fatigue Syndrome (ME/CFS) Epigenetics research holds the fascinating possibility of figuring out what shifted at the very beginning of chronic … Continue reading

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Identification of ME/CFS-associated DNA methylation patterns

Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, by Malav S. Trivedi, Elisa Oltra, Leonor Sarria, Natasha Rose, Vladimir Beljanski, Mary Ann Fletcher, Nancy  G. Klimas, Lubov Nathanson in PLoS One Vol 13, #7, p e0201066 [Published: July 23, 2018] Abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue … Continue reading

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Insights into ME/CFS phenotypes through comprehensive metabolomics

Research abstract: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics, by Dorottya Nagy-Szakal, Dinesh K. Barupal, Bohyun Lee, Xiaoyu Che, Brent L. Williams, Ellie J. R. Kahn, Joy E. Ukaigwe, Lucinda Bateman, Nancy G. Klimas, Anthony L. Komaroff, … Continue reading

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KPAX002 as a treatment for ME/CFS – disappointing trial results

  Research abstract: KPAX002 as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a prospective, randomized trial, by Jose G Montoya, Jill N Anderson, Danya L Adolphs, Lucinda Bateman, Nancy Klimas, Susan M Levine, Donn W Garvert, Jon D Kaiser … Continue reading

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ME/CFS linked to imbalanced microbiome

Columbia University Mailman School of Public Health Press release, 26 April 2017: Chronic fatigue syndrome linked to imbalanced microbiome Scientists identify abnormal levels of specific gut bacteria in individuals with chronic fatigue syndrome, including those with and without co-morbid IBS … Continue reading

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ME/CFS & Gulf War patients exhibit increased humoral responses to the enzyme dUTPase

Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Gulf War Illness (GWI) are debilitating diseases with overlapping symptomology and there are currently no validated tests for definitive diagnosis of either syndrome. While there is evidence supporting the premise that some … Continue reading

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