-
Latest News
- Research review: The enterovirus theory of disease etiology in ME/CFS
- NICE delays Roundtable – no invite for WAMES!
- Genetic research: Fine mapping of the major histocompatibility complex (MHC) in ME/CFS
- Research: A map of metabolic phenotypes in patients with ME/CFS
- UK Gov CFS research funding – Q&A in parliament
Archives
Tag Archives: immune dysregulation
Research: Pathomechanisms & possible interventions in ME/CFS
Pathomechanisms and possible interventions in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), by Øystein Fluge, Karl J. Tronstad, and Olav Mella in J Clin Invest. 2021;131(14):e150377 [doi.org/10.1172/JCI150377] July 15, 2021 Research abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease with … Continue reading
Posted in News
Tagged circulatory impairment, Dr Oystein Fluge, immune dysregulation, pathomechanism, Prof Karl Johan Tronstad, Prof Olav Mella
Comments Off on Research: Pathomechanisms & possible interventions in ME/CFS
The role of immune responses, focussing on herpes virus specificity & interferon-gamma, in Myocardial Infarction with reperfusion & in CFS
The role of immune responses, focussing on herpes virus specificity and interferon-gamma, in Myocardial Infarction with reperfusion and in Chronic Fatigue Syndrome, by Santosh Murali. Doctoral thesis, Northumbria University, 14 January 2020 Research thesis abstract: Background: Immune responses targeting … Continue reading
Posted in News
Tagged ep, Herpesvirus, immune dysregulation, immune response, interferon gamma, myocardial infarcation, Santosh Murali, T-cells
Comments Off on The role of immune responses, focussing on herpes virus specificity & interferon-gamma, in Myocardial Infarction with reperfusion & in CFS
Comparison of killer T cells in ME/CFS and MS shows immune dysregulation
Research abstract: Background: CD8+ T cells have putative roles in the regulation of adaptive immune responses during infection. The purpose of this paper is to compare the status of CD8+ T cells in Multiple Sclerosis (MS) and Chronic Fatigue Syndrome/ … Continue reading
Posted in News
Tagged CD8+ T cells, immune dysregulation, killer T cells, MS, Multiple Sclerosis
Comments Off on Comparison of killer T cells in ME/CFS and MS shows immune dysregulation
A blood test can distinguish severity CFS/ME subgroups for research
Research abstract: Immunological dysregulation is present in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), with recent studies also highlighting the importance of examining symptom severity. This research addressed this relationship between CFS/ME severity subgroups, assessing serum immunoglobulins and serum cytokines in severe … Continue reading
Posted in News
Tagged blood test, Dr Sonya Marshall-Gradisnik, immune dysregulation, immune profile, Sharni Lee Hardcastle
Comments Off on A blood test can distinguish severity CFS/ME subgroups for research
COMT gene dysfunction linked to susceptibility to infection in CFS
Research abstract: BACKGROUND: Chronic fatigue syndrome (CFS) is considered as a neuroimmunological disease but the etiology and pathophysiology is poorly understood. Patients suffer from sustained exhaustion, cognitive impairment and an increased sensitivity to pain and sensory stimuli. A subset of … Continue reading
Posted in News
Tagged COMT, HPA axis functioning, immune dysregulation, immunoglobulin, RRTI, upper respiratory tract infections
Comments Off on COMT gene dysfunction linked to susceptibility to infection in CFS
Cytokines and CFS
Abstract A major hypothesis for the cause of chronic fatigue syndrome (CFS) is immune dysregulation, thought to reflect upregulated pro-inflammatory cytokines leading to the symptoms characteristic of this illness. Because symptoms worsen with physical exertion or sleep loss, we hypothesized … Continue reading
Posted in News
Tagged immune dysregulation, PBLs, peripheral blood lymphocytes, pro-inflammatory cytokines
Comments Off on Cytokines and CFS
