Tag Archives: Cort Johnson

The Basal Ganglia, inflammation and fatigue in ME/CFS

Cort Johnson discusses the research of Dr Andrew Miller, a psychoneuroimmunologist who is interested in how immune activation affects symptoms and behaviour.  His research has mostly focused on the biological roots of depression and the effects an immune agent called interferon alpha … Continue reading

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Biomarker for fatigue could help validate CFS

Measuring Fatigue Finally? Cort Johnson asks: Has a test that objectively measures fatigue been found? Extract: How to objectively measure fatigue has dogged the Chronic Fatigue Syndrome field  for  decades. Until researchers can tell how fatigued a person really is … Continue reading

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The importance of understanding how our genes change

Extract from article by Cort Johnson: Epigenetics refers to the changes in sites in our DNA that are susceptible to change over time which can modify the expression of our genes.  Our genetic heritage, it turns out, only sets the … Continue reading

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Cognitive performance affected by poor muscle function in CFS & FM

Abstract BACKGROUND: Both good physical and cognitive functioning have a positive influence on the execution of activities of daily living. Patients with chronic fatigue syndrome (CFS) as well as patients with fibromyalgia have marked cognitive deficits. Furthermore, a good physical … Continue reading

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Cerebrospinal fluid pressure may be problem in CFS

Abstract   Objective Unsuspected idiopathic intracranial hypertension (IIH) is found in a significant minority of patients attending clinics with named headache syndromes, if it is specifically sought out. Chronic fatigue syndrome is frequently associated with headache. Could the same be … Continue reading

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NPD1 – potential drug for nerve pain in CFS

Abstract Prevalence of neuropathic pain is high after major surgery. However, effective treatment for preventing neuropathic pain is lacking. Here we report that perisurgical treatment of neuroprotectin D1/protectin D1 (NPD1/PD1), derived from docosahexaenoic acid, prevents nerve injury-induced mechanical allodynia and … Continue reading

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