Tag Archives: epigenetics

DNA Methylation & BDNF expression account for symptoms & widespread hyperalgesia in patients with CFS & FM

Posted on 07/03/2020 by wames

DNA Methylation and BDNF Expression account for symptoms and widespread hyperalgesia in patients with Chronic Fatigue Syndrome and Fibromyalgia, by Andrea Polli, Manosij Ghosh, Jelena Bakusic, Kelly Ickmans, Dora Monteyne, Brigitte Velkeniers, Bram Bekaert, Lode Godderis, Jo Nijs in Arthritis … Continue reading →

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Epigenetic components of ME/CFS uncover potential Transposable Element activation

Posted on 05/03/2019 by wames

Epigenetic components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover potential Transposable Element Activation, by  Eloy Almenar-Pérez, Tamara Ovejero PhD, Teresa Sánchez-Fito MSc, José A Espejo BSc, Lubov Nathanson PhD, Elisa Oltra PhD, in Clinical Therapeutics [Published online 23 March 2019] https://doi.org/10.1016/j.clinthera.2019.02.012 … Continue reading →

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Genome-epigenome interactions associated with ME/CFS

Posted on 01/18/2019 by wames

Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Santiago Herrera, Wilfred C de Vega, David Ashbrook, Suzanne D Vernon and Patrick O McGowan in Epigenetics 2018 [Published online: 5 Dec 2018]   Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) … Continue reading →

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System reset? Study suggests Pro-Inflammatory / Autoimmune reset in ME/CFS

Posted on 08/14/2018 by wames

Simmaron Research blog post, by Cort Johnson, 4 August 2018: System Reset? Study Suggests Pro-Inflammatory / Autoimmune Reset Occurred in Chronic Fatigue Syndrome (ME/CFS) Epigenetics research holds the fascinating possibility of figuring out what shifted at the very beginning of chronic … Continue reading →

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Identification of ME/CFS-associated DNA methylation patterns

Posted on 07/30/2018 by wames

Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, by Malav S. Trivedi, Elisa Oltra, Leonor Sarria, Natasha Rose, Vladimir Beljanski, Mary Ann Fletcher, Nancy  G. Klimas, Lubov Nathanson in PLoS One Vol 13, #7, p e0201066 [Published: July 23, 2018] Abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue … Continue reading →

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Integration of DNA methylation & health scores identifies subtypes in ME/CFS

Posted on 04/30/2018 by wames

Research abstract: Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome, by Wilfred C de Vega, Lauren Erdman, Suzanne D Vernon, Anna Goldenberg & Patrick O McGowan in Epigenomics. 2018 Apr 25. doi: 10.2217/epi-2017-0150. [Epub … Continue reading →

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Epigenetics study highlights metabolic problems in ME/CFS

Posted on 08/10/2017 by wames

Health rising blog post, by Cort Johnson, 30 July 2017: Epigenetics Study Highlights Metabolic Problems in Chronic Fatigue Syndrome (ME/CFS) There was a time that the HPA axis was “it” in chronic fatigue syndrome. More studies have been done on … Continue reading →

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Epigenetic modifications & glucocorticoid sensitivity in ME/CFS

Posted on 02/28/2017 by wames

Research abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating idiopathic disease characterized by unexplained fatigue that fails to resolve with sufficient rest. Diagnosis is based on a list of symptoms and exclusion of other fatigue-related health conditions. Despite … Continue reading →

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Changes to genes found in IBS

Posted on 01/15/2016 by wames

Research abstract: Background: Irritable bowel syndrome (IBS) is a stress-sensitive disorder. Environmental factors including stress can trigger epigenetic changes, which have not been well-studied in IBS. We performed a pilot study investigating genome-wide DNA methylation of IBS patients and healthy … Continue reading →

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The importance of understanding how our genes change

Posted on 08/28/2014 by wames

Extract from article by Cort Johnson: Epigenetics refers to the changes in sites in our DNA that are susceptible to change over time which can modify the expression of our genes.  Our genetic heritage, it turns out, only sets the … Continue reading →

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