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- Modeling disability: softly making the invisible visible
- Sleep problems in adolescents with CFS: a case-control study nested within a prospective clinical cohort
- Review of the quality control checks performed by current genome-wide & targeted-genome association studies on ME/CFS
- Systematic review of the epidemiological burden of ME/CFS across Europe: current evidence & EUROMENE research recommendations for epidemiology
- Heart rate thresholds to limit activity in ME/CFS patients (pacing): comparison of heart rate formulae
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Tag Archives: epigenetics
Epigenetic components of ME/CFS uncover potential Transposable Element activation
Epigenetic components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover potential Transposable Element Activation, by Eloy Almenar-Pérez, Tamara Ovejero PhD, Teresa Sánchez-Fito MSc, José A Espejo BSc, Lubov Nathanson PhD, Elisa Oltra PhD, in Clinical Therapeutics [Published online 23 March 2019] https://doi.org/10.1016/j.clinthera.2019.02.012 … Continue reading
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Tagged Dr Tamara Ovejero, Eloy Almenar-Pérez, epigenetics, epigenome, gene expression, José A Espejo, long-noncoding RNA, Lubov Nathanson, microRNAs, Prof Elisa Oltra, retrotransposon, Teresa Sánchez-Fito, transposable elements
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Genome-epigenome interactions associated with ME/CFS
Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Santiago Herrera, Wilfred C de Vega, David Ashbrook, Suzanne D Vernon and Patrick O McGowan in Epigenetics 2018 [Published online: 5 Dec 2018] Research abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) … Continue reading
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Tagged David Ashbrook, DNA methylation, Dr Patrick O McGowan, Dr Suzanne Vernon, epigenetics, genotypes, Santiago Herrera, Wilfred C de Vega
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System reset? Study suggests Pro-Inflammatory / Autoimmune reset in ME/CFS
Simmaron Research blog post, by Cort Johnson, 4 August 2018: System Reset? Study Suggests Pro-Inflammatory / Autoimmune Reset Occurred in Chronic Fatigue Syndrome (ME/CFS) Epigenetics research holds the fascinating possibility of figuring out what shifted at the very beginning of chronic … Continue reading
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Tagged Cort Johnson, Dr Nancy Klimas, epigenetics
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Identification of ME/CFS-associated DNA methylation patterns
Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, by Malav S. Trivedi, Elisa Oltra, Leonor Sarria, Natasha Rose, Vladimir Beljanski, Mary Ann Fletcher, Nancy G. Klimas, Lubov Nathanson in PLoS One Vol 13, #7, p e0201066 [Published: July 23, 2018] Abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue … Continue reading
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Tagged Dr Nancy Klimas, epigenetic deregulation, epigenetics, Leonor Sarria, Lubov Nathanson, Malav S Trivedi, Mary Ann Fletcher, Natasha Rose, Prof Elisa Oltra, Vladimir Beljanski
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Integration of DNA methylation & health scores identifies subtypes in ME/CFS
Research abstract: Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome, by Wilfred C de Vega, Lauren Erdman, Suzanne D Vernon, Anna Goldenberg & Patrick O McGowan in Epigenomics. 2018 Apr 25. doi: 10.2217/epi-2017-0150. [Epub … Continue reading
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Tagged Anna Goldenberg, clinical subtyping, DePaul Symptom Questionnaire, DNA methylation, Dr Patrick O McGowan, Dr Suzanne Vernon, epigenetics, Lauren Erdman, RAND-36 Short Form Survey, sub-groups, Wilfred C de Vega
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Epigenetic modifications & glucocorticoid sensitivity in ME/CFS
Research abstract: Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating idiopathic disease characterized by unexplained fatigue that fails to resolve with sufficient rest. Diagnosis is based on a list of symptoms and exclusion of other fatigue-related health conditions. Despite … Continue reading
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Tagged DNA methylation, Dr Patrick O McGowan, Dr Suzanne Vernon, epigenetics, glucocorticoid sensitivity, HPA axis functioning, innune cells, Santiago Herrera, Wilfred C de Vega
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Changes to genes found in IBS
Research abstract: Background: Irritable bowel syndrome (IBS) is a stress-sensitive disorder. Environmental factors including stress can trigger epigenetic changes, which have not been well-studied in IBS. We performed a pilot study investigating genome-wide DNA methylation of IBS patients and healthy … Continue reading
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Tagged DNA methylation, epigenetics, gene modification, IBS, Irritable bowel syndrome, methylome
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The importance of understanding how our genes change
Extract from article by Cort Johnson: Epigenetics refers to the changes in sites in our DNA that are susceptible to change over time which can modify the expression of our genes. Our genetic heritage, it turns out, only sets the … Continue reading
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Tagged Cort Johnson, DNA, epigenetics, gene expression, gene modification, Patrick O McGowan
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