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Tag Archives: Dr Olav Mella
Research: Endothelial dysfunction in ME/CFS
Endothelial dysfunction and vascular homestasis in ME/CFS A sub-study of the RituxME trial by Norwegian researchers found a problem in the blood vessels on the heart in a group of people with ME/CFS. Treatment with Rituximab caused a slight … Continue reading
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Tagged Christina Særsten Stavland, Dr Olav Mella, Dr Oystein Fluge, Elisabeth Leirgul, endothelial dysfunction, Ingrid Gurvin Rekeland, Kari Sorland, Miriam Kristine Sandvik, rituximab, RituxME, vascular dysfunction
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Research: Gut symptoms in ME/CFS
Gastrointestinal symptoms in ME/CFS The RituxME study team in Bergen, Norway have turned their attention to the little studied topic of gut symptoms in ME/CFS. Key summary: Gastrointestinal symptoms are common in ME/CFS, but there is a knowledge … Continue reading
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Tagged Dr Olav Mella, Elisabeth K Steinsvik, Functional dyspepsia, gastric accommodation, gastrointestinal symptoms, IBS, Irritable bowel syndrome, Odd Helge Giljain, Øystein Fluge, Trygve Hausken
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New study shows reduced ability to regulation of the cardiovascular system in patients with ME/CFS
Kavli Trust blog post on research into ME / CFS at Haukeland University: New study shows reduced ability to regulate the cardiovascular system in patients with ME / CFS, March 26, 2021 [Google translation of a Norwegian article] … Continue reading
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Tagged abnormal blood circulation, cardiovascular function, circulatory disorders, CycloME study, Cyclophosphamide, Dr Olav Mella, Dr Oystein Fluge, endothelial dysfunction, Haukeland University Hospital, Ingrid Gurvin Rekeland, Kari Sorland, Lis Ribu, Milada Cvancarova Småstuen, Miriam Kristine Sandvik
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Rituximab leads to B-cell depletion and remission in ME/CFS
Research abstract: Background: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab … Continue reading
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Tagged antibodies, B-cell, Dr Olav Mella, Dr Oystein Fluge, New Scientist, rituximab
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Fluge & Mella’s patent application for a CFS treatment
Excerpt from patent application: Inventors: Øystein Fluge & Olav Mella Date of publication 26 11 2014 Nitric oxide donor for the treatment of chronic fatigue syndrome. Description [0001] The present invention relates in a first aspect to a nitric oxide donor for … Continue reading
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Tagged Dr Olav Mella, Dr Oystein Fluge, Nitric oxide donor, NO donor, patent
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Rituximab interviews
Two Norwegian scientists, Øystein Fluge and Olav Mella, who have been researching the effects of an anti-lymphoma drug called Rituximab on people with ME/CFS, talked about their work on the BBC Radio Cambridgeshire programme ‘Naked Scientists’ on Sunday, 22 March. … Continue reading
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Tagged autoimmune disorders, BBC radio, blood vessels, cardiopulmonary tests, Cyclophosphamide, Dr Olav Mella, Dr Oystein Fluge, endothelial dysfunction, exercise tests, gastrointestinal disorder, gene expression, immunomodulatory drug, rituximab, Teresa Grøtan
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Update on rituximab
Drs Oystein Fluge and Olav Mella have been given 2 million Norwegian Kroners (approx. £220,000) to help fund a larger multi-centre follow-up study to confirm their findings that some people with ME had benefited from the immune modulator rituximab. This … Continue reading
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Tagged Dr Olav Mella, Dr Oystein Fluge, rituximab
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