Tag Archives: gene expression

Genes, mitochondria, autoimmunity & CFS: Prof Alan Light’s research

Health rising blog post, by Cort Johnson, 23 Feb 2017: Genes, Mitochondria, Autoimmunity and Chronic Fatigue Syndrome: The Alan Light Talk Dr. Light has said that he wants to do for fatigue what researchers have done for pain; that is … Continue reading

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A systematic review of the association between fatigue & genetic polymorphisms

Review abstract: Fatigue is one of the most common and distressing symptoms, leading to markedly decreased quality of life among a large subset of patients with a variety of disorders. Susceptibility to fatigue may be influenced by genetic factors including … Continue reading

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Mitochondrial proteins as possible biomarkers for subgroups of CFS

Research abstract: Chronic fatigue syndrome (CFS) is a debilitating and complex disorder characterized by unexplained fatigue not improved by rest. An area of investigation is the likely connection of CFS with defective mitochondrial function. In a previous work, we investigated the proteomic salivary profile … Continue reading

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Protein kinase gene dysfunction in severe CFS/ME

Research abstract: Background: The etiology and pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) are unknown. However, natural killer (NK) cell dysfunction, in particular reduced NK cytotoxic activity, is a consistent finding in CFS/ME patients. Previous research has reported significant changes … Continue reading

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Fatigue in MS and ME: similarities and differences

Cort Johnson in his blog Health rising asks if the fatigue found in MS and ME is similar or different: Simply looking at the symptoms indicated that MS is primarily a fatiguing disorder, and that MS patients may, in fact, … Continue reading

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The importance of understanding how our genes change

Extract from article by Cort Johnson: Epigenetics refers to the changes in sites in our DNA that are susceptible to change over time which can modify the expression of our genes.  Our genetic heritage, it turns out, only sets the … Continue reading

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