Tag Archives: PEM

Autonomic markers, CFS & post-exertion states

Autonomic markers, chronic fatigue syndrome, and post-exertion states, by Fred Friedberg in Journal of Psychosomatic Research Vol 127, Dec 2019, [https://doi.org/10.1016/j.jpsychores.2019.109845]   Article extracts: A large body of evidence suggests that autonomic imbalance, i.e., hyperactive sympathetic nervous system and hypoactive … Continue reading

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Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with ME/CFS

Elevated blood lactate in resting conditions correlate with post-exertional malaise severity in patients with Myalgic encephalomyelitis/Chronic fatigue syndrome by Alaa Ghali, Carole Lacout, Maria Ghali, Aline Gury, Anne-Berengere Beucher, Pierre Lozac’h, Christian Lavigne & Geoffrey Urbanski (France) in Nature Scientific … Continue reading

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Post-Exertional Malaise Is associated with hypermetabolism, hypoacetylation & purine metabolism deregulation in ME/CFS cases

Post-Exertional Malaise is associated with hypermetabolism, hypoacetylation and purine metabolism deregulation in ME/CFS cases, by Neil R McGregor, Christopher W Armstrong, Donald P Lewis and Paul R Gooley in Diagnostics 2019, 9(3), 70; [Published: 4 July 2019] https://doi.org/10.3390/diagnostics9030070 Research abstract: Post-exertional … Continue reading

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The risk of labelling CFS symptoms as unhelpful cognitive responses

The risk of labelling CFS symptoms as unhelpful cognitive responses, by Michiel Tack in Clinical Child Psychology and Psychiatry 1–2 [Published June 18, 2019]  https://doi.org/10.1177/1359104519853849   Letter to the editor: Loades, M. E., Rimes, K., Lievesley, K., Ali, S., & … Continue reading

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Abnormal blood lactate accumulation during repeated exercise testing in ME/CFS

Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome, by Katarina Lien, Bjørn Johansen, Marit B Veierød, Annicke S Haslestad, Siv K Bøhn, Morten N Melsom, Kristin R Kardel, Per O Iversen in Physiological reports vol … Continue reading

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PEM: It’s time to retire the term

PEM: It’s time to retire the term, by Pete Hanauer in The Solve ME/CFS Chronicle, Spring 2018   FOR MANY YEARS, people who suffered the pain and disruption to their lives caused by ME/CFS also suffered the indignity of being … Continue reading

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Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing

Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing, by Jerome Bouquet, Tony Li, Jennifer L Gardy, Xiaoying Kang, Staci Stevens, Jared Stevens, Mark VanNess, Christopher Snell, James Potts, Ruth R Miller, … Continue reading

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Chronotropic Intolerance: an overlooked determinant of symptoms & activity limitation in ME/CFS?

Chronotropic intolerance: an overlooked determinant of symptoms and activity limitation in myalgic encephalomyelitis/chronic fatigue syndrome?, by Todd E. Davenport,  Mary Lehnen,  Staci R Stevens,  J. Mark VanNess,  Jared Stevens and  Christopher R Snell in Front. Pediatr. 22 March 2019 Review … Continue reading

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Assessment of Post-Exertional Malaise in patients with ME & CFS

Assessment of Post-Exertional Malaise (PEM) in patients with Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS): A patient-driven survey, by Carly S Holtzman, Shaun Bhatia, Joseph Cotler and Leonard A Jason in Diagnostics 2019, 9(1), 26 [Published: 2 March 2019] … Continue reading

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Workwell’s two-day exercise tests & breaking the deconditioning dilemma in ME/CFS

Workwell’s two-day exercise tests and breaking the deconditioning dilemma in Chronic Fatigue Syndrome (ME/CFS) by Cort Johnson in Health rising blog, 19 Nov 2018 The first word in the first sentence of the paper says it all: “Concise methodological directions for … Continue reading

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